Multiple Sclerosis (GOLD) Flashcards

1
Q

What is MS?

A

Demyelination of the myelin sheaths in the brain and the spinal cord, leading to a decrease in efficiency of nerve impulses

  • subsequent plaque formation and eventual failure of nerve impulses
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2
Q

Etiology

A

Unknown

Possibly epstien-barr virus

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3
Q

Signs and Symptoms

A
  • visual problems (diplopia)
  • sensory changes
  • weakness
  • ataxia
  • balance dysfunction
  • fatigue
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4
Q

Treatments

A

Pharmacology

  • Goal is to lessen the length of exacerbations and maximize patients health
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5
Q

Which age range has the highest incidence rates?

A
  • highest incidence between 20-35 y/o
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6
Q

Which gender is more affected?

A

2x as common in Women

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7
Q

What climate is associated with a higher incidence of MS?

A

Temperate Climates

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8
Q

What ethnicity is most likely to have MS?

A

Caucasians

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9
Q

What is the most common classification of MS?

A

Relapsing-Remitting (85% of cases)

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10
Q

What laboratory or imaging studies would confirm the diagnosis early in the disease?

A

There is not a single testing procedure to diagnose MS early in the disease.

[MRI inconclusive]

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11
Q

What guidelines must be followed for a clinical diagnosis of MS to be made?

A

An individual experiences two separate attacks and shows evidence of two separate lesions.

Reliable patient history of symptoms are vital in the diagnosis of MS

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12
Q

What happens as the disease advances?

A

Exacerbations leave greater ongoing disability, length of remisions decrease

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13
Q

What PT interventions are indicated with MS

A
  • Regulation of activity level*
  • relaxation and conservation energy techniques
  • Normalization of tone*
  • adaptive/assistive device training

[These are VITAL to quality of life]

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14
Q

What part of the day should exercise be adminstered?

A

Morning patient is rested; to avoid fatigue

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15
Q

What factors can influence exacerbations?

A
  • HEAT
  • Stress
  • Infection
  • Trauma
  • Pregnancy
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16
Q

What do overall mortality rate and long-term outcomes correlate with?

A
  • age of diagnosis
  • number of attacks and exacerbations
  • frequency and duration of remissions
  • type of MS
17
Q

Those with MS mostly die from?

A

Secondary Complications [Think things due to a sedentary life style]
- disuse atrophy
- pressures sores
- contractures
- pathological fractures
- renal infection
- pneumonia

18
Q

What additional findings are likely with MS?

A
  • Emotional Lability*
  • Depression*
  • Spasticity
  • Tremor
  • paralysis
  • sexual dysfunction
  • Bowel and Bladder Incontinence
19
Q

What is Relapsing Remitting (RRMS)

A
  • Clearly Defined episodes of new or worsening symptoms
    Hallmark Sign: Period of remission between attacks
20
Q

Primary Progressive (PPMS)

A
  • Slow accumulation of disability without relapses
  • No clear periods of remission
21
Q

Secondary Progressive (SPMS)

A
  • Initially follows course of relapsing remitting
  • Remissions become less apparent and disease worsens steadily over time
22
Q

Progressive Relapsing (PRMS)

A

Steadily worsening of disease from beginning, but with clear attacks

  • Does not experience clear remissions