MSRA - Infectious Diseases Flashcards

1
Q

Campylobacter jejuni features

A

-Flu-like prodrome

-Crampy abdo pains may mimic appendicitis

-Diarrhoea may be bloody

-Complications: GB syndrome

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2
Q

Hepatitis c incubation period

A

6-9 weeks

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3
Q

Hepatitis C and breastfeeding

A

Allowed

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4
Q

Hepatitis C serology: anti-HCV

A

Previous hepatitis C infection.
Persists even if cleared virus

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5
Q

Hepatitis C serology: HCV RNA

A

Acute infection

If present >6 months = chronic hepatitis C

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6
Q

Management of hepatitis C

A

Protease inhibitors +/- ribavirin

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7
Q

Ribavirin side effects

A

Haemolytic anaemia
Cough
Teratogenic (stop 6m before getting pregnant)

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8
Q

IFN-a side effects

A

Flu-like symptoms
Depression
Fatigue
Leukopenia/thrombocytopenia

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9
Q

Treatment of confirmed Lyme disease: early disease

A

Doxycycline
(Amoxicillin in pregnancy)

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10
Q

Treatment of confirmed Lyme disease: disseminated disease

A

Ceftriaxone

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11
Q

Amsel’s criteria for diagnosis of BV

A

3 out of 4 of:
- Thin, white homogenous discharge
- Clue cells
- pH > 4.5
- Positive whiff test (potassium hydroxide)

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12
Q

Management of bacterial vaginosis

A

oral metronidazole 5-7 days

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13
Q

Chlamydia trachomatis incubation period

A

7-21 days

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14
Q

Chlamydia - when to test

A

2 weeks after possible exposure

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15
Q

Management of chlarmydia

A

Azithromycin single dose
OR
Doxycycline 7 days

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16
Q

Management of chlamydia in pregnancy

A

azithromycin, erythromycin or amoxicillin

17
Q

Chlamydia contact tracing: men with urethral symptoms

A

All contacts from four weeks prior to symptom onset

18
Q

Chlamydia contact tracing: asymptomatic men

A

All partners from last six months

19
Q

Chlamydia contact tracing: women

A

All partners from last six months

20
Q

Treatment of active tuberculosis

A

Initial phase - 2 months of RIPE

Continuation phase - 4 months of RI

21
Q

Treatment of latent tuberculosis

A

3 months of isoniazid (+ pyridoxine) and rifampicin

OR

6 months of isoniazid (with pyridoxine)

22
Q

Treatment of meningeal tuberculosis

A

Treat for 12 months, with addition of steroids

23
Q

Childhood flu vaccine - when given?

A

First dose at 2-3 years
Annually thereafter

24
Q

Neisseria gonorrhoeae incubation period

A

2-5 days

25
Q

Management of gonorrhoeae

A

IM ceftriaxone 1g

(or oral ciprofloxacin 500mg stat, if known to be sensitive)

26
Q

Commonest causes of acute food poisoning

A

-Staph aureus
-Bacillus cereus
-Clostridium perfringens

27
Q

Giardiasis infection presentation

A

Prolonged, non-bloody diarrhoea

28
Q

Shigella presentation

A

Bloody diarrhoea
Vomiting & abdominal pain

29
Q

Staph aureus food poisoning presentation

A

Severe vomiting
Short incubation period

30
Q

Bacillus cereus presentation

A

Two types:
- Vomiting within 6 hours, due to rice
- Diarrhoeal illness after 6 hours

31
Q

Amoebiasis presentation

A

Gradual onset bloody diarrhoea
Abdominal pain and tenderness
May last several weeks

32
Q

Gastroenteritis: infections with 1-6hr incubation period

A

Staph aureus
Bacillus cereus

33
Q

Gastroenteritis: infections with 112-48hr incubation period

A

Salmonella
E.coli

34
Q

Gastroenteritis: infections with 148-72hr incubation period

A

Shigella
Campylobacter

35
Q

Gastroenteritis: infections with incubation period >7 days

A

Giardiasis
Amoebiasis

36
Q

Herpes in pregnancy: primary attack >28 weeks

A

Elective caesarean section

37
Q

Trichomonas vaginalis features

A

-offensive frothy vaginal discharge
-vulvovaginitis
-strawberyy cervix
-pH >4.5

38
Q

Management of trichomonas vaginalis

A

Oral metronidazole