Antimicrobial prescribing Flashcards

1
Q

Acute epididymitis >35 + low risk STI

A

Doxycyline 100mg BD 10-14 days
or
Ofloxacin 200mg BD 14 days

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2
Q

1st line antibiotic for pyelonephritis in a child

A

Oral cefalexin

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3
Q

Antibiotic for pyelonephritis in chid if sensitivity confirmed

A

Oral co-amoxiclav

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4
Q

1st line Lyme disease

A

Doxycycline 200mg OD 21 days

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5
Q

1st choice for persistent/severe sinusitis

A

Phenoxypenicillin QDS 5 days

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6
Q

1st choice for peristent/severe sinusitis if pen-allergic

A

Doxycycline/clarithromycin/erythromycin 5 days

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7
Q

Antibiotic treatment of sinusitis if systemically very unwell/high risk

A

Co-amoxiclav 5 days

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8
Q

Travel vaccinations available free on NHS

A

Cholera
Diphtheria, polio, tetanus booster
Hep A
Typhoid

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9
Q

Antimalarial to avoid in history of depression

A

Mefloquine

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10
Q

Antimalarial taken weekly

A

Mefloquine

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11
Q

Antimalarials CI in epilepsy

A

Mefloquine
Chloroquine

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12
Q

1st line for UTI in pregnancy

A

Nitrofurantoin 100mg BD 7 days (avoid at term)

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13
Q

2nd line for UTI in pregnancy

A

Amoxicillin if known sensitive 7 days /
Cefalexin 7 days

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14
Q

1st line for cellulitis

A

Flucloxacillin 500mg QDS 5-7 days

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15
Q

Alternative for cellulitis

A

Clarithromycin / Erythromycin / Doxycyline 5-7 days

/co-amox in child

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16
Q

1st line for cellulitis on face

A

Co-amoxiclav 7 days

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17
Q

Cellulitis on face - pen-allergic adult

A

Clarithromycin + metronidazole 7 days

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18
Q

1st line gonorrhoea

A

Refer GUM
IM Ceftriaxone 1g stat

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19
Q

Gonorrhoea - only if known to be sensitive

A

Refer GUM
Ciprofloxacin 500mg stat

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20
Q

Mycoplasma pneumonia features

A

Worsening flu-like + dry cough
Bilateral changes CXR
Erythema multiforme
Haemolytic anaemia

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21
Q

Which young people are eligible for annual flu vaccine (August 2021)

A

All children aged 2-15

6m-2y in clinical risk group

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22
Q

Potential Lyme disease + history of erythema migrans

A

Treat with Doxycyline/amoxicillin

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23
Q

1st line management of Lyme disease

A

Doxycyline 100mg BD 21 days

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24
Q

Alternative antibiotic for Lyme disease

A

Amoxicillin 1g TDS 21 days

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25
Q

Potential Lyme disease - No history of erythema migrans

A

Borrelia ELISA

26
Q

Potential Lyme disease - No history of erythema migrans, ELISA negative

A

Repeat ELISA 4-6 weeks

27
Q

Potential Lyme disease - no EM, ELISA negative x2 at 12 weeks (or equivocal)

A

Immunoblot

28
Q

Acute otitis externa - 1st line

A

Analgesia, localised heat

29
Q

Acute otitis externa - 2nd line

A

Acetic acid 2% spray TDS 7 days

Neomycin + steroid drops TDS 7-14 days

30
Q

Acute otitis externa - cellulitis/extends beyond ear canal/systemic upset

A

Flucloxacillin 250-500mg QDS
Refer exclude malignant otitis externa

31
Q

1st line for PID

A

Ceftriaxone 1g IM stat + metronidazole 400mg BD 14 days + doxycycline 100mg BD 14 days

32
Q

2nd line for PID

A

Metronidazole 400mg BD 14 days + ofloxacin 400mg BD 14 days
or
Moxifloxacin 400mg OD 14 days

33
Q

1st line for TV

A

Metronidazole 400mg BD 5-7 days / 2g stat

34
Q

Live attenuated vaccines

A

BCG
MMR
Intranasal flu
Oral rotavirus
Oral polio
Oral typhoid
Yellow fever

35
Q

1st episode genital herpes (within 5 days of onset + new lesions/systemic symptoms)

A

Aciclovir 400mg TDS
Valaciclovir 500mg BD
Famciclovir 250mg TDS
5 days

36
Q

Herpes suppressive therapy (>6 per year)

A

Aciclovir 400mg BD
Aciclovir 200mg QDS
Famciclovir
Valaciclovir

37
Q

Tropical disease - ulcerating skin lesion -> mucosal involvement

A

Leishmaniasis brasiliensis

38
Q

Dengue presentation

A

Fever
Retro-orbital headache
Flushing
Maculopapular rash
Low PLT

39
Q

1st line chlamydia

A

Doxycyline 100mg BD 7 days

40
Q

2nd line chlamydia

A

Azithromycin 1g stat + 500mg OD 2 days

41
Q

Farmer: small papule on hand ->2cm, flat-topped + haemorrhagic

A

Orf

42
Q

Side effect of Atovaquone+proguanil (malarone)

A

GI upset

43
Q

Side effect of Chloroquine anti-malarial

A

Headache

44
Q

Side effects of Mefloquine (Lariam)

A

Dizziness
Neurospyschiatric
Lower seizure threshold

45
Q

1st line antibiotic for acute prostatitis

A

Ciprofloxacin 500mg BD
Ofloxacin 200mg BD
Review after 14 days

46
Q

Alternate 1st line antibiotic for acute prostatitis - if other CI

A

Trimethoprim 200mg BD
Review after 14 days

47
Q

2nd line antibiotics for acute prostatitis

A

Levofloxacin
Co-trimoxazole
Review after 14 days

48
Q

Farmer: Headache, fever, myalgia, subconjunctival haemorrhage, AKI

A

Leptospirosis

49
Q

Chancroid

A

Painful genital ulcer
Unilateral painful LN
Recent travel

50
Q

Flu -treatment for at-risk patients (prophylaxis in care home/symptom onset)

A

Oseltamivir 75mg BD 5 days

51
Q

1st choice antibiotic for AOM

A

Amoxicillin 5-7 days

52
Q

1st choice antibiotic for AOM - if pen-allergic

A

Clairthomycin / erythromycin 5-7 days

53
Q

2nd choice antibiotic for AOM

A

Co-amoxiclav 5-7 days

54
Q

Acute infective exacerbation COPD - 1st choice

A

Amoxicillin
Doxycyline
Clarithromycin
5 days

55
Q

Acute infective exacerbation COPD - high risk of treatment failure

A

Co-amoxiclav
Co-trimoxazole
Levofloxacin
5 days

56
Q

1st line for CAP (low severity: 0/1)

A

Amoxicillin 500mg TDS 5 days

57
Q

Alternatives for CAP (low severity: 0/1)

A

Doxyxcyline, clarithromycin, Erythromycin

58
Q

1st line for CAP (moderate severity in adult: 1/2)

A

Amoxicillin
(+ clarithromycin/erythromcyin if atypical)
5 days

59
Q

1st line for high-severity CAP adults/children (3/4/5)

A

Co-amoxiclav
(+ clarithyromycin/erythromycin if atypical)
5 days

60
Q

1st line for HAP

A

Co-amoxiclav 5 days + review