BNF Antibacterial Guidelines (MSRA)

Question 1

Exacerbations of chronic bronchitis

Answer 1

Amoxicillin or tetracycline or clarithromycin

Question 2

Uncomplicated CAP

Answer 2

Amoxicillin

Question 3

Possible atypical pneumonia

Answer 3

Clarithromycin

Question 4

HAP - within 5 days of admission

Answer 4

Co-amoxiclav or cefuroxime

Question 5

Uncomplicated CAP - penicillin allergic

Answer 5

-Doxycycline or clarithromycin

Question 6

Uncomplicated CAP - suspected stapholocci

Answer 6

Amoxicillin + flucloxacillin

Question 7

HAP - more than 5 days after admission

Answer 7

Piperacillin with tazobactam
OR
broad-spectrum cephalosporin (eg ceftazidime)
OR
quinolone (eg ciprofloxacin)

Question 8

Lower UTI

Answer 8

Trimethoprim or nitrofurantoin

(Alternative: amoxicillin or cephalosporin)

Question 9

Acute pyelonephritis

Answer 9

Broad-spectrum cephalosporin or quinolone

Question 10

Acute prostatitis

Answer 10

Quinolone or trimethoprim

Question 11

Cellulitis - 1st line

Answer 11

Flucloxacillin

Question 12

Cellulitis - pen allergic

Answer 12

clarithromycin, erythromycin or doxycycline

Question 13

Cellulitis - near eyes or nose

Answer 13

co-amoxiclav

Question 14

Erysipelas - 1st line

Answer 14

Flucloxacillin

Question 15

Erysipelas - pen allergic

Answer 15

clarithromycin, erythromycin or doxycycline

Question 16

Animal or human bite - 1st line

Answer 16

Co-amoxiclav

Question 17

Animal or human bite - pen allergic

Answer 17

doxycycline + metronidazole

Question 18

Mastitis and breast-feeding

Answer 18

Flucloxacillin

Question 19

Throat infections - 1st line

Answer 19

Phenoxymethylpenicillin

Question 20

Throat infections - pen allergic

Answer 20

erythromycin

Question 21

Sinusitis

Answer 21

Amoxicillin or doxycycline or erythromycin

Question 22

Otitis media - 1st line

Answer 22

Amoxicillin

Question 23

Otitis media - pen allergic

Answer 23

erythromycin

Question 24

Otitis externa (severe)

Answer 24

Flucloxacillin (erythromycin if pen allergic)

Question 25

Periapical or periodontal abscess

Answer 25

Amoxicillin

Question 26

Gingivitis: acute necrotising ulcerative

Answer 26

Metronidazole

Question 27

Gonorrhoea

Answer 27

IM ceftriaxone + oral azithromycin

Question 28

Chlamydia

Answer 28

Doxycycline or azithromycin

Question 29

Pelvic inflammatory disease

Answer 29

Oral ofloxacin + oral metronidazole Or IM ceftriaxone + oral doxycycline + oral metronidazole

Question 30

Syphilis

Answer 30

Benzathine benzylpenicillin OR Doxycycline OR Erythromycin

Question 31

Bacterial vaginosis

Answer 31

Oral or topical metronidazole, or topical clindamycin

Question 32

C.diff: first episode

Answer 32

Metronidazole

Question 33

C.diff: Second/subsequent episode

Answer 33

Vancomycin

Question 34

Campylobacter enteritis

Answer 34

Clarithromycin

Question 35

Salmonella (non-typhoid)

Answer 35

Ciprofloxacin

Question 36

Shigellosis

Answer 36

Ciprofloxacin