Derm EXTRA Flashcards
Risk factors for SCC
- Excess sun/psoralen UVA
- Actinic keratoses + Bowen’s disease
- Immunosuppression
- Smoking
- Chronic leg ulcer
- Xeroderma pigmentosum, oculocutaneous albinism
Seborrhoeic dermatitis - associated underlying conditions
HIV
Parkinsons
Seborrhoiec dermatitis - management of scalp disease - 1st line
OTC preparations containing zinc pyrithione or tar
Seborrhoiec dermatitis - management of scalp disease - 2nd line
Ketoconazole
Seborrhoiec dermatitis - face + body management
Topical antifungals: ketoconazole
Topical steroids for short periods
Erythematous facial rash sparing the nasolabial folds
Acne rosacea
Erythematous facial rash involving the nasolabial folds
Seborrhoeic dermatitis
Antibodies present in bullous pemphigoid
Anti-hemidesmosomes
Skin biopsy immunofluorescence - shows IgG and C3 at dermoepidermal junction
Bullous pemphigoid
Features of BCC (“rodent ulcer”)
Initially - Pearly, flesh-coloured papule, telangiectasia
Later - ulceration + central crater
Features of Bowen’s disease
Red, scaly patches
Slow-growing
Sun-exposed areas
Features of pyogenic granuloma (“eruptive haemangioma”)
RAPID growth
from small red/brown SPOT,
to raised red/brown spherical lesion
within days/weeks
Diagnostic test for pemphigus vulgaris
Direct immunofluorescence of skin
Features of granuloma annulare
Smooth annular flesh-coloured lesion.
No scale
Tinea corporis (ringworm): features
Annular erythematous plaque
Scale
Well defined, raised edges
May have pustules/papules
Management of granuloma annulare
Await resolution
Topical steroids if itch/cosmetic concern
Fungal body skin infection/Ringworm/Tinea corporis
- Candida possible
Fungal body skin infection/Ringworm/Tinea corporis
- 1st line for Adult
Topical Terbinafine 1% Once/Twice daily for 1 week (NWL)
Management of vitiligo
Oral steroids and azathioprine
Vitiligo vs pityriasis versicolor
Vitiligo likely to be associated with other auto-immune diseases
Features of dermatofibroma (histiocytoma)
Benign fibrous skin lesion
Pinch test > forms a dimple
Features of BCC
Sun-exposed - head & neck
Pearly papule
Prominent telangiectasia
Later ulcerates > crater
BCC - commonest treatment
Surgery
Features of keratoacanthoma
Dome shaped
Symmetrical
Keratotic/necrotic core
Rapid growth (months)
Treatment of keratoacanthoma
Urgent excision to exclude SCC
Features of SCC
Initially scaly erythematous patch
Treatment of SCC
Surgical excision
Treatment of metastatic melanoma
Pembrolizumab (PD-1 receptor blocker)
Features of actinic keratoses
Erythematous plaques
Sun-exposed area
Treatment of actinic keratoses
Topical 5-FU/diclofenac/salicyclic acid
Risk factors for SCC
- Excess sun/psoralen UVA
- Actinic keratoses + Bowen’s disease
- Immunosuppression
- Smoking
- Chronic leg ulcer
- Xeroderma pigmentosum, oculocutaneous albinism
Seborrhoeic dermatitis - associated underlying conditions
HIV
Parkinsons
Seborrhoiec dermatitis - management of scalp disease - 1st line
OTC preparations containing zinc pyrithione or tar
Seborrhoiec dermatitis - management of scalp disease - 2nd line
Ketoconazole
Seborrhoiec dermatitis - face + body management
Topical antifungals: ketoconazole
Topical steroids for short periods
Erythematous facial rash sparing the nasolabial folds
Acne rosacea
Erythematous facial rash involving the nasolabial folds
Seborrhoeic dermatitis
Antibodies present in bullous pemphigoid
Anti-hemidesmosomes