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Derm EXTRA Flashcards

1
Q

Risk factors for SCC

A
  • Excess sun/psoralen UVA
  • Actinic keratoses + Bowen’s disease
  • Immunosuppression
  • Smoking
  • Chronic leg ulcer
  • Xeroderma pigmentosum, oculocutaneous albinism
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2
Q

Seborrhoeic dermatitis - associated underlying conditions

A

HIV

Parkinsons

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3
Q

Seborrhoiec dermatitis - management of scalp disease - 1st line

A

OTC preparations containing zinc pyrithione or tar

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4
Q

Seborrhoiec dermatitis - management of scalp disease - 2nd line

A

Ketoconazole

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5
Q

Seborrhoiec dermatitis - face + body management

A

Topical antifungals: ketoconazole

Topical steroids for short periods

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6
Q

Erythematous facial rash sparing the nasolabial folds

A

Acne rosacea

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7
Q

Erythematous facial rash involving the nasolabial folds

A

Seborrhoeic dermatitis

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8
Q

Antibodies present in bullous pemphigoid

A

Anti-hemidesmosomes

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9
Q

Skin biopsy immunofluorescence - shows IgG and C3 at dermoepidermal junction

A

Bullous pemphigoid

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10
Q

Features of BCC (“rodent ulcer”)

A

Initially - Pearly, flesh-coloured papule, telangiectasia

Later - ulceration + central crater

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11
Q

Features of Bowen’s disease

A

Red, scaly patches
Slow-growing
Sun-exposed areas

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12
Q

Features of pyogenic granuloma (“eruptive haemangioma”)

A

RAPID growth
from small red/brown SPOT,
to raised red/brown spherical lesion
within days/weeks

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13
Q

Diagnostic test for pemphigus vulgaris

A

Direct immunofluorescence of skin

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14
Q

Features of granuloma annulare

A

Smooth annular flesh-coloured lesion.
No scale

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15
Q

Tinea corporis (ringworm): features

A

Annular erythematous plaque
Scale
Well defined, raised edges
May have pustules/papules

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16
Q

Management of granuloma annulare

A

Await resolution
Topical steroids if itch/cosmetic concern

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17
Q

Fungal body skin infection/Ringworm/Tinea corporis
- Candida possible

A
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18
Q

Tinea Corporis / “Ringworm” / Fungal body skin infection
- 1st line for Adult

A

Topical terbinafine 1% once or twice daily for at least 1 week. Continue up to 2 weeks.

✔ NICE CKS (Fungal skin infection – body and groin, Jan 2022)
✔ NWL ICB (2023–2024 formulary)

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19
Q

Management of vitiligo

A

Oral steroids and azathioprine

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20
Q

Vitiligo vs pityriasis versicolor

A

Vitiligo likely to be associated with other auto-immune diseases

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21
Q

Features of dermatofibroma (histiocytoma)

A

Benign fibrous skin lesion
Pinch test > forms a dimple

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22
Q

Features of BCC

A

Sun-exposed - head & neck
Pearly papule
Prominent telangiectasia
Later ulcerates > crater

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23
Q

BCC - commonest treatment

A

Surgery

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24
Q

Features of keratoacanthoma

A

Dome shaped
Symmetrical
Keratotic/necrotic core
Rapid growth (months)

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25
Treatment of keratoacanthoma
Urgent excision to exclude SCC
26
Features of SCC
Initially scaly erythematous patch
27
Treatment of SCC
Surgical excision
28
Treatment of metastatic melanoma
Pembrolizumab (PD-1 receptor blocker)
29
Features of actinic keratoses
Erythematous plaques Sun-exposed area
30
Treatment of actinic keratoses
Topical 5-FU/diclofenac/salicyclic acid
31
Risk factors for SCC
- Excess sun/psoralen UVA - Actinic keratoses + Bowen's disease - Immunosuppression - Smoking - Chronic leg ulcer - Xeroderma pigmentosum, oculocutaneous albinism
32
Seborrhoeic dermatitis - associated underlying conditions
HIV Parkinsons
33
Seborrhoiec dermatitis - management of scalp disease - 1st line
OTC preparations containing zinc pyrithione or tar
34
Seborrhoiec dermatitis - management of scalp disease - 2nd line
Ketoconazole
35
Seborrhoiec dermatitis - face + body management
Topical antifungals: ketoconazole Topical steroids for short periods
36
Erythematous facial rash sparing the nasolabial folds
Acne rosacea
37
Erythematous facial rash involving the nasolabial folds
Seborrhoeic dermatitis
38
Antibodies present in bullous pemphigoid
Anti-hemidesmosomes
39
Skin biopsy immunofluorescence - shows IgG and C3 at dermoepidermal junction
Bullous pemphigoid
40
Features of BCC ("rodent ulcer")
Initially - Pearly, flesh-coloured papule, telangiectasia Later - ulceration + central crater
41
Features of Bowen's disease
Red, scaly patches Slow-growing Sun-exposed areas
42
Features of pyogenic granuloma ("eruptive haemangioma")
RAPID growth from small red/brown SPOT, to raised red/brown spherical lesion within days/weeks
43
Diagnostic test for pemphigus vulgaris
Direct immunofluorescence of skin
44
Features of granuloma annulare
Smooth annular flesh-coloured lesion. No scale
45
Features of tinea corporis
Annular erythematous plaque, with raised edge and scale
46
Management of granuloma annulare
Await resolution Topical steroids if itch/cosmetic concern
47
Management of tinea corporis
Oral fluconazole
48
Management of vitiligo
Oral steroids and azathioprine
49
Vitiligo vs pityriasis versicolor
Vitiligo likely to be associated with other auto-immune diseases
50
Features of dermatofibroma (histiocytoma)
Benign fibrous skin lesion Pinch test > forms a dimple
51
Features of BCC
Sun-exposed - head & neck Pearly papule Prominent telangiectasia Later ulcerates > crater
52
BCC - commonest treatment
Surgery
53
Features of keratoacanthoma
Dome shaped Symmetrical Keratotic/necrotic core Rapid growth (months)
54
Treatment of keratoacanthoma
Urgent excision to exclude SCC
55
Features of SCC
Initially scaly erythematous patch
56
Treatment of SCC
Surgical excision
57
Treatment of metastatic melanoma
Pembrolizumab (PD-1 receptor blocker)
58
Features of actinic keratoses
Erythematous plaques Sun-exposed area
59
Treatment of actinic keratoses
Topical 5-FU/diclofenac/salicyclic acid
60
Multiple scaly lesions, 2-4 weeks after sore throat
Guttate psoriasis
61
1st line for mild impetigo
Topical hydrogen peroxide 1%
62
2nd line for mild impetigo
Topical fusidic acid
63
1st line for extensive impetigo
Oral flucloxacillin
64
Treatment of extensive impetigo if pen-allergic
Oral erythromycin
65
Drugs which induce TEN
Phenytoin Carbemazepine Allopurinol Sulphonamides Penicillins NSAIDs
66
1st line treatment of dermatophyte nail infection
Oral terbinafine
67
1st line treatment of candidal nail infection
Topical amorolfine
68
Dermovate (Clobetasol propionate 0.05%)
Very potent
69
Cutivate (Fluticasone propionate 0.05%)
Potent
70
Betnovate (Betamethasone valerate 0.1%)
Potent
71
Betnovate RD (Betamethasone valerate 0.025%)
Moderate
72
Eumovate (Clobetasone butyrate 0.05%)
Moderate
73
Hydrocortisone 0.5-2.5%
Mild
74
Management of periorifical dermatitis
Topical or oral antibiotics
75
1st line for mild rosacea
Topical metronidazole
76
1st line for scalp psoriasis
Topical potent corticosteroid (Betamethasone 0.1%) Up to 4wks
77
2nd line for scalp psoriasis (after 4wks)
Different formulation of corticosteroid +/- Agent to remove scale
78
3rd line for scalp psoriasis (after 4 wks)
Calcipotriol-betamethasone or Vitamin D analogue (if mild-mod)
79
Multiple scaly lesions, 2-4 weeks after sore throat
Guttate psoriasis
80
1st line for mild impetigo
Topical hydrogen peroxide 1%
81
2nd line for mild impetigo
Topical fusidic acid
82
1st line for extensive impetigo
Oral flucloxacillin
83
Treatment of extensive impetigo if pen-allergic
Oral erythromycin
84
Drugs which induce TEN
Phenytoin Carbemazepine Allopurinol Sulphonamides Penicillins NSAIDs
85
1st line treatment of dermatophyte nail infection
Oral terbinafine
86
1st line treatment of candidal nail infection
Topical amorolfine
87
Dermovate (Clobetasol propionate 0.05%)
Very potent
88
Cutivate (Fluticasone propionate 0.05%)
Potent
89
Betnovate (Betamethasone valerate 0.1%)
Potent
90
Betnovate RD (Betamethasone valerate 0.025%)
Moderate
91
Eumovate (Clobetasone butyrate 0.05%)
Moderate
92
Hydrocortisone 0.5-2.5%
Mild
93
Management of periorifical dermatitis
Topical or oral antibiotics
94
1st line for mild rosacea
Topical metronidazole
95
1st line for scalp psoriasis
Topical potent corticosteroid (Betamethasone 0.1%) Up to 4wks
96
2nd line for scalp psoriasis (after 4wks)
Different formulation of corticosteroid +/- Agent to remove scale
97
3rd line for scalp psoriasis (after 4 wks)
Calcipotriol-betamethasone or Vitamin D analogue (if mild-mod)

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