MSK 12 - Muscles-II Flashcards
What are some key histological differences between cardiac and skeletal muscle?
Facts to know about the structures of cardiac myocytes that can be seen on a light micrograph.
What are atrial cardiac myocytes? What is their purpose?
What are intercalated discs? Discuss basic function, structure, and composition.
Facts to know about the transverse and lateral components of intercalated discs.
How are sarcomeres of cardiac muscle fibers different from skeletal muscle fibers?
The sarcomeres themselves are the same but in skeletal muscle the sarcomeres form a banded pattern while they form branched networks in cardiac muscle
How is the sarcoplasmic reticulum of cardiac muscle different from skeletal?
Facts to know about the tranverse tubular system of cardiac muscle.
Discuss how cardiac muscle repairs damaged cells.
Facts to know about Purkinje Fibers.
How does smooth muscle generally appear on a light micrograph?
What is unique about the appearance of smooth muscle cell nuclei?
What is an important function of smooth muscle cells besides contracting?
Secreting a connective tissue matrix
What types of matrix proteins do smooth muscle cells secrete?
Discuss the regenerative capacity of smooth muscle cells.
Label and describe what this is an image of.
Discuss the arrangement and composition of myofilaments in a smooth muscle cell.
What is a dense body in a smooth muscle cell? What purpose does it serve?
What are the three ways smooth muscle contraction is regulated?
What are myofibroblasts? Where are they usually located?
Specialized connective tissue cells that are in between fibroblasts and smooth muscle cells, in phenotype. They are located beneath the epithelium of mucosal lingings such as the genitourinary and GI tract.
What do myofibroblasts arise from and what stimulates this differentiation?
Fibroblasts are activated to myofibroblasts-MF by TGFß1,
What are the primary functions of myofibroblasts?
Facts to know about myoepithelial cells.
