MSK 12 - Muscles-II

Question 1

What are some key histological differences between cardiac and skeletal muscle?

Answer 1

Question 2

Facts to know about the structures of cardiac myocytes that can be seen on a light micrograph.

Answer 2

Question 3

What are atrial cardiac myocytes? What is their purpose?

Answer 3

Question 4

What are intercalated discs? Discuss basic function, structure, and composition.

Answer 4

Question 5

Answer 5

Question 6

Facts to know about the transverse and lateral components of intercalated discs.

Answer 6

Question 7

How are sarcomeres of cardiac muscle fibers different from skeletal muscle fibers?

Answer 7

The sarcomeres themselves are the same but in skeletal muscle the sarcomeres form a banded pattern while they form branched networks in cardiac muscle

Question 8

How is the sarcoplasmic reticulum of cardiac muscle different from skeletal?

Answer 8

Question 9

Facts to know about the tranverse tubular system of cardiac muscle.

Answer 9

Question 10

Answer 10

Question 11

Discuss how cardiac muscle repairs damaged cells.

Answer 11

Question 12

Facts to know about Purkinje Fibers.

Answer 12

Question 13

How does smooth muscle generally appear on a light micrograph?

Answer 13

Question 14

What is unique about the appearance of smooth muscle cell nuclei?

Answer 14

Question 15

What is an important function of smooth muscle cells besides contracting?

Answer 15

Secreting a connective tissue matrix

Question 16

What types of matrix proteins do smooth muscle cells secrete?

Answer 16

Question 17

Discuss the regenerative capacity of smooth muscle cells.

Answer 17

Question 18

Label and describe what this is an image of.

Answer 18

Question 19

Discuss the arrangement and composition of myofilaments in a smooth muscle cell.

Answer 19

Question 20

What is a dense body in a smooth muscle cell? What purpose does it serve?

Answer 20

Question 21

Answer 21

Question 22

What are the three ways smooth muscle contraction is regulated?

Answer 22

Question 23

Answer 23

Question 24

What are myofibroblasts? Where are they usually located?

Answer 24

Specialized connective tissue cells that are in between fibroblasts and smooth muscle cells, in phenotype. They are located beneath the epithelium of mucosal lingings such as the genitourinary and GI tract.

Question 25

What do myofibroblasts arise from and what stimulates this differentiation?

Answer 25

Fibroblasts are activated to myofibroblasts-MF by TGFß1,

Question 26

What are the primary functions of myofibroblasts?

Answer 26

Question 27

Facts to know about myoepithelial cells.

Answer 27