Module 8: Immune Deficiency Disorders

Question 1

Primary immune deficiencies are present at

Answer 1

birth

Question 2

5 categories of primary immune deficiencies

Answer 2

Cellular
Humoral
Combined
Phagocytic
Complement

Question 3

Cellular immune deficiency is characterized by

Answer 3

severe viral, fungal, parasitic or protozoan infections

Thymus is absent

Question 4

Humoral immune deficiency is characterized by

Answer 4

agammaglobinemia and recurrent bacterial infections

Question 5

Combine immune deficiency is characterized by

Answer 5

sever deficiencies of both T and B cells with recurrent overwhelming infections

Question 6

Secondary immune deficiencies occur sometime ____ ____ and are caused by

Answer 6

after birth

Caused by natural or artificial factors (extreme illness, infection disease or immunosuppressive drugs)

Question 7

Assessment of cellular immune function

Answer 7

peripheral lymph count
T cell count
Delayed hypersensitivity skin testing
Lymphokine production
Biopsy of lymph nodes (decreased in size)

Question 8

Assessment of humoral immune function

Answer 8

Ig quantification and typing
B cell count (CD19 pos)
Ab titres
Biopsy of bone marrow and lymph nodes