Module 11: Transplant Immunology Obj. 8

Question 1

3 ways of immunosuppression

Answer 1

chemical immunosuppressants
Biological agents
Radiation

Question 2

Chemical immune suppressants work in 3 ways

Answer 2

Inhibition of mitosis
Inhibition of protein synthesis
Anti-inflammatories decrease the number of circulating lymphs and decrease phagocytic and cytotoxic abilities of macrophages

Question 3

Biological agents

Answer 3

Ab directed against immune cells

Question 4

Radiation

Answer 4

depletes patients lymphs prior to transplant

Often used prior to bone marrow transplant