Module 7: Type IV Flashcards
1
Q
Another name for type IV
A
Delayed hypersensitivity
Symptoms occur 24-48hrs post exposure
2
Q
What is this reaction due to
A
Involvement of T cells (NO ANTIBODIES)
3
Q
Type IV steps
A
T cell is exposed to Ag
T cell is activated and releases lymphokines (Migration inhibition factor is most important)
MIF attracts macrophages to the antigenic site and prevents them from leaving
4
Q
3 examples of Delayed hypersensitivity
A
Contact sensitivity Granulomatous Hypersensitivity (monocytes unable to phagocytose ingested particles) Tuberculin reaction (skin test)
