Module 22 Flashcards

Changes in Signal Transdustion Pathways

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1
Q

Mutations

A

Heritable changes in genetic material
They can produce altered receptor proteins that interfere with cell communication

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2
Q

Signalling disruptions

A

Changes to or replacements for the signaling molecules can interrupt proper cell communication

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3
Q

What can activate inhibit receptors

A

Chemicals in foods and drugs

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4
Q

What happens when inhibit receptors are attached to the receptor

A

influence rest of cell response
Abnormal or unexpected responses by the target cell

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5
Q

What happens with cell disruption

A

homeostasis is disrupted resulting in poor health for an organism

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6
Q

Agonist

A

any ligand that binds to a receptor and causes a response

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7
Q

Antagonist

A

any ligand that binds to a receptor and inhibits a response/ transduction pathway

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8
Q

Endogenous ligands

A

Ligands produced by the body

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9
Q

Exogeneous ligands

A

Ligands from outside the body
Can affect signaling pathways
Some mimic endogenous ligands, producing typical cell response
Some over-stimulate the signal transduction pathways, resulting in stronger responses

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10
Q

Albuterol

A

Used to open airways of the lungs
Agonist of the adrenaline receptors

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11
Q

Where is albuterol from

A

The extract of leaves

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12
Q

What happens when the exogenous agonist of a receptor is bound more tightly

A

The ligand stays attached longer, resulting in a longer lasting response, and a greater overall response

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13
Q

How can exogenous ligands caused altered cell responses

A

By coming in the cell at the wrong time, or at the wrong level

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14
Q

Why is caffeine an antagonist

A

Binds to adenosine receptors but does not cause it change shape and so it remains inactive
It suppresses the response to feel drowsy

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15
Q

Where does aspirin come from

A

the bark of a shrub called the GENUS SPIRAEA

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16
Q

Where does taxol come from and do

A

Treats cancers and is from the pacific yew tree

17
Q

Where does digitalis come from and do

A

Used to treat heart failure and comes from a common flower in English gardens

18
Q

What do the sequence of DNA bases create

A

The structure of proteins, including signaling molecules, receptor proteins, and other protiens

19
Q

What can a mutation do to a DNA sequence

A

It can lead to a change in the amino acid sequence of a protein, affecting the protein’s shape and function

20
Q
A