Module 13 Endocrine System Flashcards

1
Q

14 Glands in endocrine system:

A

Pituitary, pineal, thyroid, parathyroid (4), thymus, adrenal (2), pancreas, and gonads (2)

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2
Q

hypothalamus

A

produces 8 hormones–6 are local that regulate the production of hormones by the anterior pituitary gland; 2– oxytocin and antidiuretic hormone (ADH) are transported to posterior pituitary where they are stored until needed elsewhere

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3
Q

pineal gland

A

located on the roof of the third ventricle of the brain, posterior to hypothalamus; secretes serotonin by day and converts it to melatonin at night

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4
Q

leptin

A

hormone secreted by adipose tissue

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5
Q

oxytocin

A

hypothalamic hormone that stimulates the uterus to contract

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6
Q

prostaglandin

A

hormone present in many tissues but first isolated from prostate gland

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7
Q

hypophysis

A

AKA pituitary gland; suspended from hypothalamus

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8
Q

pituitary gland

A

two components: adenohypophysis (large anterior lobe) and neurohypophysis (smaller posterior lobe);

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9
Q

adenohypophysis

A

produces 6 hormones: follicle-stimulating hormones (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH aka thyrotropin), adrenocorticotropic hormone (ACTH), prolactin (PRL), and growth hormone (GH or somatotropin)

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10
Q

tropic hormones

A

hormones that stimulate other endocrine glands to produce their hormones

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11
Q

neurohypophysis

A

two hormones: oxytocin (OT), antidiuretic hormone (ADH aka vasopressin)

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12
Q

GnRH

A

gonadotropin-releasing hormone

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13
Q

acromegaly

A

enlargement of the head, face, hands, and feet due to excess GH as an adult

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14
Q

diabetes insipidus

A

excretion of large amounts of dilute urine as a result of inadequate ADH production

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15
Q

prognathism

A

condition of a forward-projecting jaw

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16
Q

prolactinoma

A

prolactin-producing tumor

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17
Q

osmolality

A

concentration of a solution

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18
Q

Methods of radiation therapy:

A

gamma knife stereotactic radiosurgery, proton beam, therapy, external beam radiation

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19
Q

thyroid hormones

A

triiodothyronine (T3) and thyroxine (T4)– thyroid hormone refers to T3 and T4 collectively; hormones produced in respose to thyroid-stimulating hormone (TSH) from the anterior pituitary gland; functions: stimulates almost every tissue in the body to produce proteins, increases the amount of O2 that cells can use, and controls the body’s metabolic rate

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20
Q

calcitonin

A

thyroid hormone that moves calcium from blood to bones

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21
Q

thyroid storm

A

medical crisis and emergency due to excess thyroid hormones

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22
Q

graves disease

A

autoimmune disorder in which an antibody stimulates the thyroid to produce and secrete excessive quantities of thyroid hormones into the blood

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23
Q

goiter

A

enlargement of the thyroid gland

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24
Q

exophthalmos

A

protrusion of the eyeball as seen in hyperthyroidism

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25
Q

Hashimoto disease

A

autoimmune disease of the thyroid gland

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26
Q

cretinism

A

condition of severe congenital hypothyroidism

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27
Q

parathyroid gland

A

usually 4 and are partially embedded in the posterior surface of the thyroid gland; secrete parathyroid hormone (PTH) in response to hypocalcemia

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28
Q

hyperparathyroidism

A

excess PTH due to enlarged glands ; more common than hypo; 4 abnormalities: osteopenia, hypercalcemia, nephrolithiasis, and depression, fatigue, and coma due to hypercalcemia

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29
Q

thymus

A

located in mediastinum; large in children and decreases in size until it is mostly fibrous tissue; secretes hormones that stimulate the production of T lymphocytes

30
Q

DiGeorge syndrome

A

genetic immunodeficiency disorder which the thymus is underdeveloped or absent at birth

31
Q

adrenal glands

A

aka suprarenal glands; adrenal cortex (outer layer) synthesizes more than 25 steroid hormones collectively called adrenocortical hormones, corticosteroids, or corticoids; adrenal medulla (inner layer) secretes catecholamines

32
Q

corticosteroids

A

3 types:
1. glucocorticoids- stimulate fat and protein catabolism and helps regulate blood glucose levels (ex. hydrocortisone)
2. mineralocorticoids- promotes sodium retention and potassium excretion by kidneys (ex. aldosterone)
3. Sex steroids:
androgens and estrogens

33
Q

Addison disease

A

autoimmune disease leading to decreased production of adrenocortical steroids

34
Q

catecholamines

A

prepare the body for physical activity by raising blood pressure, increaseing circulation to the muscles, increase pulmonary blood flow, and stimulate gluconeogenesis; ex. epinephrine (adrenaline) and norepinephrine

35
Q

DHEA

A

precursor to testosterone; produced in the adrenal cortex

36
Q

adrenogenital syndrome

A

hypersecretion of androgens from the adrenal gland

37
Q

Cushing syndrome

A

hypersecretion of cortisol by the adrenal cortex

38
Q

facies

A

facial expression and features characteristic of a specific disease

39
Q

hirsutism

A

excessive body and facial hair

40
Q

pheochromocytoma

A

adenoma of the adrenal medulla secreting excessive catecholamines

41
Q

Pancreas

A

mostly functions as a exocrine gland that secretes digestive juices into the duodenum; however, also has pancreatic islets (islets of Langerhans) which are cluster of endocrine cells grouped around blood vessels

42
Q

3 types of cells with in pancreatic islets:

A
  1. alpha- secrete glucagon in response to low blood glucose
  2. beta- secrete insulin in response to high blood glucose
  3. delta- secrete somatostatin which acts within the pancreas to inhibit the secretion of glucagon and insulin
43
Q

glucagon

A

secreted by alpha cells; functions: in the liver- stimulates gluconeogenesis, glycogenolysis, and the release of glucose into the blood stream, in adipose tissue- stimulate fat catabolism and the release of free fatty acids

44
Q

insulin

A

secreted by beta cells; opposite of glucagon; functions: in muscle and fat cells- encourage absorption of glucose to store glycogen and fat, in liver- stimulate the conversion of glucose to glycogen and to inhibit the conversion of noncarbohydrates to glucose

45
Q

gluconeogenesis

A

formation of glucose from noncarbohydrate sources

46
Q

glycogenolysis

A

conversion of glycogen to glucose

47
Q

somatostatin

A

hormone that inhibits release of growth hormone and insulin

48
Q

DM

A

diabetes mellitus; syndrome characterized by hyperglycemia resulting rom an absolute or relative impairment of insulin secretion and/or insulin action.

49
Q

insulin resistance

A

decreased insulin effectiveness in stimulating glucose uptake by tissues and in restraining hepatic glucose production

50
Q

hyperosmolar

A

marked hyperglycemia without ketoacidosis

51
Q

ketone

A

chemical formed in uncontrolled diabetes or in starvation

52
Q

metabolic acidosis

A

decreased pH in blood and body tissues as a result of an upset in metabolism

53
Q

paresthesia

A

an abnormal sensation; for example, tingling, burning, pricking

54
Q

polydipsia

A

excessive thirst

55
Q

polyphagia

A

excessive eating

56
Q

glycosylated hemoglobin

A

Hb A1c

57
Q

microalbuminuria

A

presence of very small quantities of albumin in urine that cannot be detected by conventional urine testing

58
Q

crin/o

A

secrete

59
Q

kal/i

A

potassium

60
Q

-dipsia

A

thirst

61
Q

extirpation

A

taking or cutting out solid matter within a body part without removing the entire body part; ex. blood clot or non-cancerous tumor

62
Q

removal

A

removing or taking out a device in or on a body part; ex. removal of pancreatic drain

63
Q

repair

A

restoring the body part to its normal structure; ex. thymoplasty

64
Q

transplantation

A

surgical procedure where the surgeon puts in a living body part from a person or animal into another person; could be all or part of a body part; ex. thymus gland transplant

65
Q

control

A

ex. “control” the bleeding

66
Q

antidiuretics

A

names: DDAVP, Desmopressin, Pitressin, Pressyn, Vasopressin

67
Q

Antithyroids

A

names: Lucol’s solution, Methimazole, Sodium iodine solution, Tapazole

68
Q

Corticosteroids

A

names: Cortisone, Depo-Medrol, Hydrocortisone, Prednisone, Solu-Medrol, Triamcinolone

69
Q

Growth hormone replacements

A

names: Humatrope, Norditropin, Somatropin

70
Q

Insulins

A

names: Humalog, Humulin R, Lantus, Novolin R, Novolog

71
Q

oral antidiabetics

A

Glipizide, Glucophage, Glocotrol, Metformin

72
Q

Thyroid supplements

A

Levo-T, Levothyroxine, Levoxyl, Synthroid, Triostate