MJ Hepatic Lecture Flashcards

1
Q

what does albumin do?

A

helps fluid stay in vasculature

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2
Q

what important plasma protein does the liver produce?

A

albumin

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3
Q

why is the liver a primary organ for metastasis of intestinal cancer?

A

filters all blood from GI system

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4
Q

pancreas is a _______ and _______ gland

A

exocrine and endocrine

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5
Q

1º fxn of pancreas

A

exocrine secretion of digestive enzymes

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6
Q

pancreas’ endocrine fxn

A

secretion of glucagon and insulin

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7
Q

gallbladder is a reservoir for ______

A

bile

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8
Q

3 biggest concern symptoms for liver disease

A

confusion, edema, ascites

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9
Q

liver metabolizes and detoxifies _________

A

ammonia

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10
Q

________ crosses the blood-brain barrier

A

ammonia

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11
Q

what activities increase portal HTN?

A

eating and coughing

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12
Q

cornerstone of treatment for liver disease

A

rest

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13
Q

liver disease pts have decreased _______ abilities

A

clotting

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14
Q

tremor of hand when wrist is extended seen in liver disease

A

asterixis

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15
Q

liver ______ in size and weight with aging

A

decreases

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16
Q

what happens to blood flow in liver with aging?

A

diminished

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17
Q

6 liver disease complications

A
  1. jaundice
  2. cirrhosis
  3. portal HTN
  4. hepatic encephalopathy
  5. hepatorenal syndrome
  6. ascites
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18
Q

what is ascites?

A

accumulation of fluid in peritoneal cavity causing swelling of abdomen

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19
Q

final pathway of chronic, progressive inflammation of liver

A

cirrhosis

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20
Q

what is cirrhosis?

A

replacement of normal tissue w fibrotic tissue

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21
Q

2 most common causes of cirrhosis

A

alc abuse/HBV

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22
Q

pressure that indicates portal HTN

A

over 6 mmHg

23
Q

barriers to blood flow _______ portal HTN

24
Q

varices

A

abnormal blood vessel

25
portal HTN results in ______ in what two locations?
varices rectum and gastroesophageal (most serious)
26
when is portal pressure the highest?
at night and after a meal
27
why can't you lie a pt with ascites in supine?
won't be able to breathe
28
ascites is a result of ______
portal htn
29
position that pt with ascites should be in
high fowler - head of bed raised 18-20 in
30
acute or chronic inflammation of the liver caused by virus, chemical, drug rxn or alc abuse
hepatitis
31
how many different types of hep?
6 - ABCDEG
32
generic term for any rapidly progressing form of liver inflammation that results in hep encephalopathy within a few weeks of developing infection
fulminant hepatitis - F
33
most cases of chronic hep are __________
asymptomatic
34
what quadrant will hep pts have pain in?
upper R
35
prognosis of hep depends on....
development of cirrhosis
36
hep can _____ before symptoms appear
spread
37
how is HAV transmitted?
oral-fecal route
38
major outbreaks of HAV occur when?
when people consume contaminated water or food
39
is HAV acute or chronic?
acute
40
how to transmit HBV
needle stick or mucosal
41
most common cause of chronic hep and liver CA
HBV
42
major risk factor for liver CA
HCV
43
how to transmit HCV
injection drug use
44
HCV is often...
asymptomatic
45
most common type of chronic hep
HCV
46
you have to have ____ in order to have ____
B, D
47
high incidence of HDV among these two groups
IVDA and sexually active people
48
if you have HDV, you are more likely to develop....
HFV and chronic active hep/cirrhosis
49
how to transmit HEV
contaminated water via oral-fecal route
50
is HEV fatal?
na
51
HEV occurs in __________
developing countries
52
prevalent in african countries
HGV
53
how is HGV transmitted?
injection, sexually