Edema Flashcards
______ isolates tissue that’s damaged and allows for it to heal in isolation
edema
lymph vessels run ______ to artery/veins
parallel
lymph vessels anchor to…
CT
collecting vessels of lymphatic system
venous system
2 primary lymphatic structures
- thymus
2. bone marrow
what generates lymphocytes?
thymus
5 secondary lymphatic structures
- nodes
- spleen
- adenoids
- skin
- tonsils
tertiary lymphatic structure
tissues that import between lymphocytes from blood and lymph
tertiary structures don’t kick in until…
foreign antigen is present and immune response turns on
purpose of lymphatic system:
pick up _________ and return to circulation
plasma proteins
purpose of lymphatic system:
_________ for fluid overload
safety valve
purpose of lymphatic system:
maintenance of _________ of EC environment
homeostasis
purpose of lymphatic system:
filters ___________ and prevents spread of infection
interstitial fluid
path of one way lymph flow
lymph lymph nodes interstitial space lymphatic capillaries large collecting vessel venous circulation
what drives this system?
heart
what % of body’s fluids are handled by lymph system
10%
edema vs lymphedema
edema: amt of fluid in IS space is greater than normal
lymphedema: accumulation in interstitium caused by destruction of lymph channels, nodes, vessels
3 effects of edema
- inc pressure on sensory system
- dec ROM
- dec venous flow (DVT)
3 pressure gradients
- hydrostatic
- interstitial
- osmotic
hydrostatic gradient goes from ____ –> _____
high to low pressure
hydrostatic gradient influenced by (2)
BP and gravity
hydrostatic gradient flow =
out of capillaries
osmotic gradient goes from ____–> _______
low to high
osmotic gradient flow =
into capillaries
osmotic gradient driven by
balance of protein and sodium along with water
interstitial gradient flow =
out of capillaries
is it neg or pos in interstitial space?
negative
interstitial gradient ______ –> _______
pos –> neg
cap –> IS
edema creates what kind of charge in IS?
positive; thus disrupting flow
hydrostatic is usually ____ osmotic
greater than
what does the balance of hydrostatic/osmotic pressure result in?
dec fluid in IS and proper exit through veins
the balance of interstitial fluid is dependent on what 3 things?
- permeability of cap membrane
- pressure gradients
- intact lymph systems
exss = hydrostatic pressure _____
increase
hydrostatic pressure increase =
inc arterial flow
pressure in veins = _____ of venous return
blockage
transudate vs exudate
transudate - stays within system
exudate -weeps
stage I is _____, whereas stage II is _________
reversible, irreversible
example of stage II
post mastectomy
often a complication of stage III
cellulitis
elephatiasis is stage ___
III
described as a bilateral, symmetrical, flabby swelling of the legs that arises from deposition of adipose tissue starting at the hips and ending at the ankles, like riding breeches
lipedema
edema caused by venous insufficiency
venous edema
Lymphedema caused by an impaired lymph flow due to malignant tumor
malignant lymphedema
edema caused by thyroid dysfunction
myxedema