Miscellaneous Antigens

Question 1

Vel (034) system associated with absence of

Answer 1

SMIM1

Question 2

CD59 (035) system based on

Answer 2

CD59-deficient child who formed an alloantibody with CD59 specificity

Question 3

CD59 (035) system function

Answer 3

Complement-regulatory glycoprotein, also known as MIRL

Question 4

Augustine (036) system first described in the serum of

Answer 4

Mrs. Augustine, a black woman in 1967

Question 5

Kanno (037) system associated with

Answer 5

Prion protein (PrPC) linked to Creutzfeldt-Jakob disease (CJD)

Question 6

SID (038) system antigen found in

Answer 6

Saliva, urine, meconium

Question 7

Sda antigen named for

Answer 7

Sid, head of the maintenance department at the Lister Institute

Question 8

Sda soluble form found in urine as

Answer 8

Tamm-Horsefall/Uromodulin glycoprotein

Question 9

CHOLINE TRANSPORTER-LIKE PROTEIN 2 (CTL2/SLC44A2) (039) widely expressed on

Answer 9

Neutrophils, lymphocytes, platelets

Question 10

Human neutrophil antigen HNA3 is located on

Answer 10

CTL2

Question 11

Alloantibodies to HNA3a associated with

Answer 11

Transfusion-related acute lung injury (TRALI)

Question 12

PEL (040)

Answer 12

Antigen: MER2, Gene: Monoclonal antibody, Prevalence: High, Clinical Significance: Anti-PEL antibodies are rare, not implicated in HDFN

Question 13

MAM (041)

Answer 13

Antigen: MAM, Gene: Monoclonal antibody, Prevalence: Very high frequency, Clinical Significance: Anti-MAM is rare, recognizes an antigen of high frequency

Question 14

EMM (042)

Answer 14

Antigen: EMM, Gene: Monoclonal antibody, Prevalence: High, Clinical Significance: Anti-EMM antibodies are rare, not implicated in HDFN

Question 15

ABCC1 (043)

Answer 15

Antigen: ABCC1, Gene: ATP-binding cassette (ABC) transporter, Prevalence: High, Clinical Significance: Anti-ABCC1 antibodies are rare, not implicated in HDFN

Question 16

ER (044)

Answer 16

Antigen: ER, Gene: Erythrocyte receptor family, Prevalence: High, Clinical Significance: Anti-ER antibodies are rare, not implicated in HDFN

Question 17

Receptor of Haemophilus influenza that prefers HBA to enter RBCs

Answer 17

Anwj

Question 18

HLA class I antigens detectable on mature RBCs

Answer 18

HLA Antigens on RBCs

Question 19

Includes Bga (HLA-B7), Bgb (HLA-B17), Bgc (HLA-A28)

Answer 19

Bg (Benett-Goodspeed)