Blood Donation Flashcards
Compatibility testing and blood component preparation location
Blood Bank - Transfusion Service Center
Donor screening, blood drawing, and testing location
Blood Center (Donation Center)
Blood collection location
Blood Collection Unit
Safer donation type
Autologous Donors
Volume of anticoagulant for for 450 mL blood donation
+/- 10% = 63 mL
Volume of anticoagulant for 500 mL blood donation
+/- 10% = 70 mL
Maximum blood donation volume including testing samples
525 mL
Autologous blood collection timing before surgery
5 to 6 weeks before surgery
Latest blood collection time before surgery
No later than 72 hours before surgery
Acute Normovolemic Hemodilution collection of whole blood with crystalloid___ or _____ colloid
crystalloid (3:1) or colloid (1:1) infusion
Intraoperative Collection
Collection of shed blood from the surgical site, processing, and reinfusion
Postoperative Salvage
Collection of blood from a surgical site drainage tube for reinfusion
Allogeneic Blood Donation
Blood given to another individual
Law for Voluntary non-remunerated donors, directed donors, and paid donors
7719 National Blood Services Act of 1994 regulation
Voluntary Non-Remunerated Donors
Donors who give blood voluntarily without compensation
Directed Donors
Donors who give blood for a designated recipient
Paid Donors
Donors who receive compensation for donating blood
Autologous blood use
Treats surgical blood loss in specific cases to avoid homologous transfusions
Autologous blood use alternative
Used when compatible allogeneic blood is unavailable
Irradiation of blood units
Required if donor is a blood relative
Purpose of blood unit irradiation
Prevents graft versus host disease
Graft versus host prevention mechanism
Inactivates viable T cells to stop attack on patient’s cells
Pheresis donor interval
At least 2 days; no more than twice a week or 24 times a year
Platelet count for first donation
Not required on the first donation
Platelet count for frequent donations
Required if donation interval is <4 weeks; must be >150,000/μL
Plasma and platelet removal limit
500 mL per procedure; 9600 mL per year for donors >175 lbs
Aspirin or aspirin-containing medication deferral
48 hours
Plavix (clopidogrel) or Ticlid (ticlopidine) deferral
14 days
Deferral after WB donation or >100 mL RBC loss during pheresis
8 weeks
First product collected by apheresis
Plasma
Infrequent plasma donation frequency
No more than once every 4 weeks
Frequent plasma donation interval
At least 48 hours; no more than two donations per 7-day period
RBC loss limit in frequent donations
25 mL/week or 200 mL in 8 weeks
Serum total protein requirement
At least 6 g/dL
Leukapheresis purpose
Collects leukocytes, specifically granulocytes
Therapeutic dose for leukapheresis
At least 1 x 10^10 granulocytes daily for 5 days
Agents used to increase leukocyte volume
HES, corticosteroids, recombinant hematopoietic growth factors