Misc Liver Dz of Dogs and Cats Flashcards

1
Q

What is cholangiohepatitis secondary to?

A

Biliary obstruction, ascending infection, immune-mediated liver damage

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2
Q

What other conditions is cholangiohepatitis usually seen in conjunction with?

A

IBD and/or pancreatitis

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3
Q

What is a major clinical sign of cholangiohepatitis?

A

Icterus

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4
Q

How will bloodwork be affected by cholangiohepatitis?

A

Elevated GGT and elevated bilirubin

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5
Q

What histopathologic changes are assoc. w/cholangiohepatitis?

A

Infiltration of neutrophils into portal areas

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6
Q

How do you treat cholangiohepatitis?

A

Urodeoxycholic acid, Vit E, milk thistle for 2mo w/abx

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7
Q

How do you surgically decompress a cholangiohepatitis 2* to biliary obstruction?

A

biliary-to-intestinal diversion

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8
Q

What is the prognosis for cholangiohepatitis?

A

Fair in dogs, half of cats do poorly (3mo MST)

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9
Q

How do you ddx cholangiohepatitis from lymphocytic portal hepatitis?

A

Histopath

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10
Q

What histopathologic changes are assoc. w/lymphocytic portal hepatitis?

A

Infiltration of lymphocytes and plasma cells into portal areas but not bile ducts

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11
Q

What is the prognosis for lymphocytic portal hepatitis?

A

Good (MST 2yr)

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12
Q

What is fatty liver syndrome?

A

Hepatic lipidosis

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13
Q

What liver enzyme is NOT elevated w/hepatic lipidosis?

A

GGT

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14
Q

How will hepatic lipidosis appear on ultrasound?

A

Enlarged w/hyperechoic parenchyma

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15
Q

What will you see on cytology of hepatic lipidosis?

A

Clusters of hepatocytes w/cytoplasmic lipid droplets

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16
Q

How do you treat hepatic lipidosis?

A

Feeding tube immediately, Vit K1, L-carnitine

17
Q

Why should a feeding tube be placed in a hepatic lipidosis patient as soon as possible?

A

Nutritional support decreases mortality from 90% to 30%

18
Q

How does neomycin and lactulose help treat hepatic lipidosis?

A

Decreases hepatic encephalopathy