micro Flashcards

1
Q

mycoplasma pneumonia

A
  • no cell wall
  • tracheobronchitis and walking pneumonia
  • elevated reticulocyte count
  • increased LDH via cold agglutinins via IgM crosslinks, then compliment binding to RBC causes hemolysis
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2
Q

e coli virulence factor

A

Lipid A - induces release of pyrogens (fever, hypotension, septic shock)

also P Fimbriae

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3
Q

campylobacter jejuni

A
  • gram negative comma shaped
  • in intestinal tract of animals (undercooked chicken)
  • bloody diarrhea
  • oxidase positive
  • reactive arthritis
  • causes guillon barre - ascending paralysis
  • autoimmune response causing demyelination(endometrial) of nerves (opposite of botulism)
  • invasive
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4
Q

neisseria pili

A

attaches to nasopharyngeal epithelial cells

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5
Q

undergoes antigenic variation

A

neisseria

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6
Q

HBsAG

A

chronic infection is >6 months

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7
Q

anti HBsAg

A

confers long term immunity

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8
Q

plasmodium falciparum

A

-malaria
-treat with atovaquone and proguinil
-peripheral blood smear with giemsa staining shows multiple small rings representing developing trophozoites

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9
Q

yersinia pestis

A

safety pin appearance on staining

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10
Q

pertussis toxin

A

bark like cough
causes increased intracellular cAMP through inactivation of Gi subunit

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11
Q

green discharge from penis

A

neisseria gonhorrea

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12
Q

rash on palms and soles

A

CARS

coxsackie A
rickettsia
syphilis

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13
Q

multiple enhancing ring lesions

A

toxoplasmosis
treat with sulfazadine and pyrimethamine

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14
Q

curved bacterium

A

h pylori
campylobacter
vibrio cholera

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15
Q

steeple chase sign

A

croup

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16
Q

hep b DNA

A

double stranded but transcribed into partially double stranded DNA

17
Q

thumbprint sign

A

epiglottis - ex haemophilius

18
Q

acute hepatitis A infection

A

spotty necrosis with hepacyte ballooning, eosinophilic apoptotic hepatocytes, with fever, anorexia, and dark colored urine

19
Q

Organism with Gamma hemolysis

A

Enterococcus, strep gallolyticus

20
Q

Organism bile soluble

A

Strep pneumonia

21
Q

Organism bile insoluble

A

Strep viridans

22
Q

Mulberry shaped intracytoplasmic inclusions

23
Q

bacteriodes fragilis

A

anaerobic gram negative bacillus that can cause periappendiceal abscess

24
Q

virulence of bordatella pertussis

A

loss of ciliated respiratory epithelial cells

25
methadone silver staining
pjp pneumonia
26
blastomyces has ___ formation in the lungs
granuloma
27
has a low infectious dose
shigella, because it can survive in acidic pH
28
how to treat PJP pneumonia
TMP-SMX
29
phospholipid splitting
clostridium perfringes
30
blueberry muffin rash
congenital CMV
31
sensorineural hearing loss in newborn
congenital CMV
32
Toxoplasmosis congenital defects
Intracranial calcification, chorioretinitis, hydrocephalus
33
bilateral, hemorrhagic necrosis of the inferior and medial temporal lobes
HSV encephalitis
34
HIV protease inhibitors
Inhibit HIV protease from cleaving gag-pol polyproteins, results in formation of immature Non infectious virions due to impaired production of functional viral proteins
35
VWF platelets
Normal
36
babesiosis vector
ixodes tick - causes intraerythrocytic inclusions
37
CMV retinitis is treated with
gancyclovir