MHC- Class 2&3 Flashcards
1
Q
What type of peptide is in the MHC 2 molecule?
A
Antigenic peptide
2
Q
What 2 domains form the antigen binding site of the MHC 2 molecules?
A
Alpha 1 and Beta 1
3
Q
What type of molecule does the Alpha 2 and Beta 2 domains have a binding site for?
A
CD4
4
Q
How do MHC molecules bind to peptides?
A
Through anchor residues
5
Q
Each MHC molecule can bind to ________ different peptides
A
Many
6
Q
___ MHC molecule can present to many antigenic peptides
A
1
7
Q
How many amino acids do MHC 2 molecules have for antigenic peptides?
A
13-25
8
Q
What MHC molecules are NOT directly related to antigen presentation?
A
3
9
Q
What 2 domains form the antigen-binding groove of MHC 2 molecules?
A
Alpha 1 and Beta 1