Antigen- Last Part Flashcards
Complex but NOT _______ molecules are normally good antigens
Simple
What tends to be poor antigens because of their wide distribution, relative simplicity, structure instability, and rapid metabolism?
Lipids
What are lipids linked to proteins or polysaccharides- good or bad antigens?
Good
What MHC molecules can present lipid, lipoprotein, and glycolipid antigens to lymphocytes?
CD1
What are very poor antigens because they are relatively simple, flexible, and are very rapidly degraded?
Mammalian nucleic acids
What are structurally different from that found in eukaryotes with many unmethylated CpG sequences, meaning they can stimulate potent immune responses?
Microbial nucleic acids
What determines whether lymphocytes in a host can or cannot respond to an antigen?
MHC molecules
What have antigenicity but not immunogenicity?
Hapten
What are small molecules that are immunogenicity only when bound to other large molecules?
Hapten
What is the immunogenic molecule to which haptens are attached?
Carrier
What are commonly used in research for mechanistic study of the immune system?
Haptens
What is antigenic, but not immunogenic
Dinitrophenol (DNP)
What is both antigenic and immunogenic?
Dinitriphenol (DNP) + Carrier protein
What type of protein helps induce an immune response to a hapten?
Carrier