Complement System- MAC

Question 1

In the lectin and classical pathways, what is not covalently bound to the cell surface during the activation of C5?

Answer 1

C5b

Question 2

During the alternative pathway of the activation of C5, what is the last component that is enzymatically cleaved?

Answer 2

C5

Question 3

Forming the membrane attack complex (MAC)- what binds C6 and C7?

Answer 3

C5b

Question 4

Forming the membrane attack complex (MAC)- C5b67 complexes bind to the membrane via?

Answer 4

C7

Question 5

Forming the membrane attack complex (MAC)- What binds to the complex and inserts into the cell membrane?

Answer 5

C8

Question 6

What is the first complement component that inserts into the pathogen cell membrane?

Answer 6

C8

Question 7

Forming the membrane attack complex (MAC)- What molecules bind to the complex and POLYMERIZE?

Answer 7

C9

Question 8

Forming the membrane attack complex (MAC)- How many molecules bind to form a pore in the pathogen membrane?

Answer 8

10-16