Complement System- Alternative Flashcards
1
Q
What pathway can be activated by membrane-bound C3b generated from lectin pathway or classical pathway?
A
Alternative
2
Q
Why is the alternative pathway an amplifier for the lectin and classical pathway?
A
Both L and C generate C3b
3
Q
Alternative pathway can be activated by?
A
Spontaneous hydrolysis of C3
4
Q
What factor binds to the pathogen surface during C3 convertase in the alternative pathway?
A
Factor D
5
Q
What are destroyed as fast as they are generated in healthy animals?
A
C3b
6
Q
What stabilizes C3 convertase complex on the pathogen surface?
A
Properdin (factor P)
