Mesotelioma Flashcards

1
Q

Qual principal associação ocupacional de mesotelioma?

A
  • Ocupacional: > 70% dos casos tem associação com asbestos (telha, caixa dagua, cimento, navio)
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2
Q

Como é feito o diagnostico?

A

Padrão ouro: Videotoracoscopia

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2
Q

Quais os subtipos histologicos de mesotelioma?

A

1- Epitelioide
2- sarcomatoide
3- Mistos

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3
Q

Qual IHQ do mesotelioma?

A

1- Calretinina
2- WT-1
3- D2-40
4- Vimentina
- Perda de BAP-1
6- Mesotelina

> TTF-1 e CEA negativo nos epitelioides

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4
Q

Quais diagnosticos diferenciais?

A

1- Metastases pleurais
2- Sarcoma sinovial
3- Leiomiossarcoma
4- Carcinoma sarcomatoide
5- Linfomas
6-Infeccoes

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5
Q

Quais fatores prognosticos do mesotelioma?

A

1- Histologia ( sarcomatoides pior prognostico
2- Estadadiamento ( III e IV)
3- Sexo Masc
4- tabagismo associado
5- ECOG
6- Fatores lab ruins ( anemia, plaquetose, leucocitose)

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6
Q
A
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