Menstruation Disorders Flashcards
What are the 3 phases of the Menstrual Cycle?
- Follicular (days 1-14)
- Ovulatory (days 14-17)
- Luteal (days 15-28
LH and FSH promote ovarian synthesis of what two things?
- Follicles
2. Ovum (egg)
What do the follicles secrete? At what phase?
Estrogen; follicular
What is Primary Dysmenorrhea?
Lower ab pain
When does Primary Dysmenorrhea occur?
During Ovulatory phase
What is the pathophysiology of Primary Dysmenorrhea?
- Release of prostaglandins + leukotriens
- Increased vasopressin
- Stimulation of vasoconstriction + uterine contraction
What are some RX that are excluded from Primary Dysmenorrhea?
- Warfarin
- Heparin
- Lithium
Which OTC therapies risk harm to the fetus in pregnancy for Primary Dysmenorrhea?
Ibuprofen + Naproxen
Which OTC therapies is excreted into breast milk?
Naproxen + Aspirin
What is the preferred first-line therapy for Primary Dysmenorrhea?
NSAIDS
What are some pharmacological Tx for Premenstrual Syndrome?
If mild, NSAIDS + Pyridoxine (Vit. B6) + Calcium w/ Vit. D (which can prevent PMS symptoms) + Magnesium
Which Tx for Premenstrual Syndrome causes constipation?
Calcium w/ Vit. D
Which Tx for Premenstrual Syndrome causes diarrhea?
Magnesium
What are the OTC diuretics for PMS?
- Ammonium chloride
- Caffeine in combination
- Pamabrom in combination
Should you recommend Pamprin or Midol for PMS?
No, NSAIDs are better