Hair Loss Flashcards
What percentage of peeps experience hair loss at some point in life?
50%
What are the main categories of hair loss?
- Non-scarring alopecia
2. Scarring alopecia
What chromosomes are affected in hair loss?
- 3q26 + 20p11 in AGA
2. HLA genes
What is the most common form of hair loss?
Androgenetic Alopecia
90% of hair follicles are in the ____/____ stage
anagen/growth
In the pathophysiology of hair loss in Androgenetic Alopecia, the anagen-to-telogen ratio (increases/decreases)
decreases (from 12:1 to 5:1)
In the pathophysiology of hair loss in Androgenetic Alopecia, anagen phase becomes (longer/shorter) and telogen phase becomes (longer/shorter)
Anagen - shorter
Telogen - longer
Anagen vs Telogen hair
Which is more loosely anchored?
Telogen
As telogen hairs are shed, there is a gradual replacement with ____-like hair
vellus (short + fine)
A build up of ______ causes hair to become thin
Dihydrotestosterone (DHT)
______ is the primary repressor for hair growth
Dihydrotestosterone (DHT)
Loss of all scalp hair is known as Alopecia _______
totalis
Loss of all body and scalp hair, including eyebrows and eyelashes is known as Alopecia _______
universalis
How could you test for hair loss?
- Biopsy of scalp
- Daily hair loss count
- Hair-pull test
What is the hair-pull test?
- Hold 40-60 hairs between thumb and forefinger and pull
- Positive test = more than 10% of hairs are removed
which suggest androgenetic alopecia is not involved - All non-Androgenetic hair loss should be referred to PCP
What age group is excluded from self-care?
<18 yrs old
What are some random info on exclusions of self-care?
- Fever/inflammation occuring 6 months before hair loss began
- Loss of eyebrows/eyelashes
- Change in appearance of nails
- Pregnant/breastfeeding, recent d/c of BC pills or post-partum
What is Minoxidil MOA?
- K+ channels open and vasodilation
2. Stimulates anagen phase
What is there to expect with use of Minoxidil?
- Increase of hair loss first few weeks of treatment
- Take up to 4-6 months to see results
- Once RX is stopped, hair loss returns to pre-treatment levels
Who should not use Minoxidil?
- Pt w/ history of heart problems
2. Ppl who treated their hair with hair color/relaxants
What is the brand name of Minoxidil?
Rogaine
FDA approves the use of what RX for hair loss?
Just Minoxidil
What solution % does Minoxidil come in?
2% + 5%
What is the direction of use of Minoxidil?
Men - 1 capful of foam BID
Women - 1 capful of foam QD
What are some major counseling tips of Minoxidil solution?
- 1 mL BID, NEVER double
- It takes 2-4 hours for drug to penetrate scalp
- Apply 2-4 hrs before bedtime
- Do NOT dry w/ blow dryer
What is another RX that can be used in combination w/ Minoxidil for improved results?
Finasteride (Proscar)
What is a complimentary therapy for hair loss?
Saw Palmetto
