Hair Loss

Question 1

What percentage of peeps experience hair loss at some point in life?

Answer 1

50%

Question 2

What are the main categories of hair loss?

Answer 2

1. Non-scarring alopecia

2. Scarring alopecia

Question 3

What chromosomes are affected in hair loss?

Answer 3

1. 3q26 + 20p11 in AGA

2. HLA genes

Question 4

What is the most common form of hair loss?

Answer 4

Androgenetic Alopecia

Question 5

90% of hair follicles are in the ____/____ stage

Answer 5

anagen/growth

Question 6

In the pathophysiology of hair loss in Androgenetic Alopecia, the anagen-to-telogen ratio (increases/decreases)

Answer 6

decreases (from 12:1 to 5:1)

Question 7

In the pathophysiology of hair loss in Androgenetic Alopecia, anagen phase becomes (longer/shorter) and telogen phase becomes (longer/shorter)

Answer 7

Anagen - shorter

Telogen - longer

Question 8

Anagen vs Telogen hair

Which is more loosely anchored?

Answer 8

Telogen

Question 9

As telogen hairs are shed, there is a gradual replacement with ____-like hair

Answer 9

vellus (short + fine)

Question 10

A build up of ______ causes hair to become thin

Answer 10

Dihydrotestosterone (DHT)

Question 11

______ is the primary repressor for hair growth

Answer 11

Dihydrotestosterone (DHT)

Question 12

Loss of all scalp hair is known as Alopecia _______

Answer 12

totalis

Question 13

Loss of all body and scalp hair, including eyebrows and eyelashes is known as Alopecia _______

Answer 13

universalis

Question 14

How could you test for hair loss?

Answer 14

1. Biopsy of scalp
2. Daily hair loss count
3. Hair-pull test

Question 15

What is the hair-pull test?

Answer 15

1. Hold 40-60 hairs between thumb and forefinger and pull
2. Positive test = more than 10% of hairs are removed
   which suggest androgenetic alopecia is not involved
3. All non-Androgenetic hair loss should be referred to PCP

Question 16

What age group is excluded from self-care?

Answer 16

<18 yrs old

Question 17

What are some random info on exclusions of self-care?

Answer 17

1. Fever/inflammation occuring 6 months before hair loss began
2. Loss of eyebrows/eyelashes
3. Change in appearance of nails
4. Pregnant/breastfeeding, recent d/c of BC pills or post-partum

Question 18

What is Minoxidil MOA?

Answer 18

1. K+ channels open and vasodilation

2. Stimulates anagen phase

Question 19

What is there to expect with use of Minoxidil?

Answer 19

1. Increase of hair loss first few weeks of treatment
2. Take up to 4-6 months to see results
3. Once RX is stopped, hair loss returns to pre-treatment levels

Question 20

Who should not use Minoxidil?

Answer 20

1. Pt w/ history of heart problems

2. Ppl who treated their hair with hair color/relaxants

Question 21

What is the brand name of Minoxidil?

Answer 21

Rogaine

Question 22

FDA approves the use of what RX for hair loss?

Answer 22

Just Minoxidil

Question 23

What solution % does Minoxidil come in?

Answer 23

2% + 5%

Question 24

What is the direction of use of Minoxidil?

Answer 24

Men - 1 capful of foam BID

Women - 1 capful of foam QD

Question 25

What are some major counseling tips of Minoxidil solution?

Answer 25

1. 1 mL BID, NEVER double
2. It takes 2-4 hours for drug to penetrate scalp
3. Apply 2-4 hrs before bedtime
4. Do NOT dry w/ blow dryer

Question 26

What is another RX that can be used in combination w/ Minoxidil for improved results?

Answer 26

Finasteride (Proscar)

Question 27

What is a complimentary therapy for hair loss?

Answer 27

Saw Palmetto