Memory (T) Flashcards

1
Q

The difference between a lobectomy and a lobotomy is that…

A

Lobectomy: removal of lobe
Lobotomy: separation of lobe

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2
Q

Retrograde amnesia is

A

Loss of memory from before the damage

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3
Q

With anterograde amnesia, you can’t ______ memories

A

Form new

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4
Q

HM’s performance on the BLOCK-TAPPING test suggested he had….

A

Global amnesia (all senses)

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5
Q

HM’s procedural/episodic/semantic memory was still intact

A

Procedural

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6
Q

What did the case of HM suggest regarding memory storage?

A

Different modes of storage for STM and LTM (and explicit and implicit)

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7
Q

What is cerebral ischemia?

A

Interruption of blood supply to brain

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8
Q

What is the specific vitamin deficiency that accompanies Korkasoff’s?

A

Thiamine

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9
Q

Korkasoff’s Syndrome begins as anterograde, but can progress…

A

To retrograde in its later stages

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10
Q

Test for animal LTM?

A

Delayed non-match sample test

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11
Q

The delayed non-match to sample test tests the assumption that…

A

Amnesia from medial temporal lobe damage results from hippocampal damage

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12
Q

Why was the delayed non-match to sample test repeated in rats?

A

In monkeys, HC lesions involves damaging larger portions of cortex as well

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13
Q

In rats, bilateral surgical removal of the hippocampus produced…

A

Moderate/no deficits in the test

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14
Q

People, monkeys and rats with ischemic damage have severe deficits in…

A

Object recognition

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15
Q

People, monkeys and rats with ischemic damage have severe deficits in object recognition. Why is this?

A

Ischemia –> hyperactivity of glutamate

Widespread damage outside of hippocampus too

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16
Q

After the findings from the rat Mumby test, it was concluded that object recognition loss is as a result of….

A

Extrahippocampal damage (produced by ischemia NOT lobectomy)

17
Q

Effects of hippocampal lesions on spatial memory (rats) were shown in

A

Morris water maze

Randal arm maze test

18
Q

Main function of the hippocampus

A

Spatial memory

19
Q

3 memory effects of hippocampal lesions

A

Spatial memory
Reference memory
Working memory

20
Q

What are hippocampal place cells?

A

Neurons that fire when a subject is in a specific location

21
Q

Place cells suggest that our brains have a ….

A

Spatial map

22
Q

Hippocampal Place Cells respond to location in combination with

A

Other features of environment

23
Q

What is the cognitive map theory?

A

HC constructs/stores maps of external world from sensory input

24
Q

How does the hippocampus play a role in episodic memory?

A

Spatial context plays critical role in acquiring/recalling episodic memory

25
Q

Hebb’s Theory

A

Synpatic changes underlying LTM seem to be same changes underlying LTP

26
Q

How long does LTP last?

A

Long time - months after multiple stimulations

27
Q

LTP only develops if

A

Presynaptic neuron firing is followed by postsynaptic neuron firing (co-occurrence)

28
Q

3 stages of LTP

A

Induction
Maintenance
Expression