Membrane Transport Flashcards
What are the two types of channel proteins? What are the characteristics of each?
Leakage channels (always open)
Gated channels (controlled by chemical or electrical signals)
Characteristics of carrier and channel proteins
Exhibit specificity
Are saturable (rate is determined by number of carriers or channels)
Can be regulated in terms of activity and quantity
Hypertonic
A solution having greater solute concentration than that if the cytosol
How does Ca2+ ATPase work?
- Calcium and ATP binding
- Phosphorylation of aspartate
- Conformational change
- Calcium release
- Dephosphorylation
- Conformational change
Sodium- potassium pump. Type of transport
Active; Antiport
Membrane permeability equation
Membrane permeability = lipid solubility/ molecular size
Types of Membrane Transport
Simple Diffusion
Carrier- mediated transport
Vesicular Transport
Channel mediated facilitated diffusion
Through a channel protein; mostly ions
Selected on basis of size and charge
Types of simple diffusion
Through lipid bilateral
osmosis
Transmembrane integral proteins transport specific ____________ proteins.
polar
Examples of antiport carriers
- Na+- H+
- Na+- Ca2+
Edematous patients
Patients that are swollen because of water is retained in their tissues
When solutions of different osmolarity are separated by a membrane, osmosis occurs until _______ is reached.
Equilibrium
Types of vesicular transport
Endocytosis
Exocytosis
Certain lipophobic molecules use _____ proteins or _______ proteins.
Carrier; channel
Changing the _______ of the lipid layer can increase or decrease membrane permeability.
composition
How does the sodium potassium pump work?
- Sodium and ATP binding
- Phosphorylation of aspartate
- Conformational change
- Sodium release; potassium binding
- Dephosphorylation and conformational change
- Potassium release
What substances are membrane permeable?
Gases, small uncharged polar molecules
What substance are not membrane permeable?
Large uncharged polar molecules, ions, and charged polar molecules