Membrane Structure and Transport Flashcards
What can TEM show in membrane?
2 layers
What can freeze fracturing show in membrane?
can separate the layers and reveal membrane
are plasma membranes symmetrical?
no - because of proteins on one side or the other = can see with freeze fracture - E face is different from P face
different phospholipid/glycolipid vs. inside and outside
how is the head linked to talk in phospholipids?
PO4 group - phosphatydylcholine
what is the backbone of the phospholipid?
glycerol
what are the hydrocarbon, hydrophobic tails also?
fatty acids!
what do saturated fatty acids do to the plasma membrane?
decrease fluditiy
what things increase fluidity of the plasma membrane?
loose packing of hydrocarbon tails, high temps, decrease cholesterol (cholesterol prevents extremes)
where are integral membrane proteins?
embedded in the bilayer - divide into transmembrane and lipid linked - covalent
where are transmembrane proteins?
they are integral proteins that extend the entire plasma membrane
where are peripheral member proteins
associated with the surface of the bilayer
aka protein attached - weak bonds
what are proteoglycans?
membrane proteins which have more than one long polysacchride chains attached
how can you restrict membrane protein movement?
anchor to cell, link to ECM molecules, link to surface proteins of another cells, diffusion barriers
what is a hypertonic solution?
high concentration of solute
what is a hypotonic solution?
low concentration of solute
