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Histology > Digestive Glands 2 > Flashcards

Digestive Glands 2 Flashcards

1
Q

what is the parenchymal cell of liver?

A

hepatocyte - liver is the second largest organ in the body!

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2
Q

what is Glisson’s capsule?

A

the capsule of the liver that subdivides the liver into lobes and lobules

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3
Q

what is special about the portal v. contents?

A

nutrient laden (heavy) blood from the alimentary tract and spleen

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4
Q

what is porta hepatis aka portal triad?

A

region where the hepatic a. and portal v. ENTER

hepatic ducts LEAVE

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5
Q

what do the sublobular veins collect blood from?

A

the central v. of each classical liver lobule

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6
Q

what is the hepatic v. made up of?

A

union of many sublobular veins

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7
Q

what are the three types of liver lobules

A

classical = hexagonal
portal = triangular
liver acinus of Rappenport = diamond

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8
Q

what does the portal area (triad) contain?

A

branches of the portal v.
hepatic a.
bile duct
lymph vessel

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9
Q

what composes the bulk of the lobule?

A

plates of hepatocytes

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10
Q

where are bile canaliculi? what do they do?

A

between neighboring heptaocytes

convey bile to canals of Herring

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11
Q

what do the canals of Herring do?

A

deliver bile ducts in portal areas at the periphery of the classical lobule

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12
Q

what re sinusoids? waht do they do?

A

endothelial-lined spaced between neighboring plates of hepatocytes
they recieve blood from the vessels in teh portal areas and dliver it to the central vein

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13
Q

what is interesting about the endothelial cells that line the sinusoids?

A

large fenestrations - discontinuous

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14
Q

what are Kupffer Cells? what do they do?

A

present within endothelial lining

phagocytic cells that are derived from moncytes

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15
Q

what is the space of Disse? function?

A

subendothelial space between liver cells and the lining cells of the sinusoids

exchange material betwen blood stream and hepatocytes
no basal lamina!

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16
Q

what does the space of Disse contain?

A

stellate - shaped fat storing cells - store vit. A
reticular fibers - maintain arch. of sinusoids
non myelinated nerve fibers
short, blunt Mv of hepatocytes

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17
Q

what is the portal lobules?

A

triangle - 3 apices are neighboring central v.

portal area in center of triangle

18
Q

what is the liver acinus of Rappenport?

A

wtf?

19
Q

what do hepatocytes have?

A 
rER and sER
mitochondria
golgi regions
lysosomes and peroxisomes - repped
lipid droplets 
glycogen
20
Q

Proteins produced by hepatocytes are synthesized in the rough endoplasmic reticulum (RER),

A

explains why hepatocyte lesions or starvation lead to a decrease in the amounts of albumin, fibrinogen, and prothrombin in a patient’s blood.

21
Q

what makes up intrahepatic bile duct?

A

bile canaliculi
cholangioles
canals of herring- liine by low cuboidal cells
bile ducts - lined by single cuboidal cells

22
Q

what are hepatic bile ducts?

A

recieve bile from the main ducts of the liver

major ducts are right andleft

23
Q

what is teh exocrine function of the liver?

A

prduction of bile

24
Q

what is bile made of?

A

bilirubin, bile acids, cholsterol, phospholipids, ions and water

25
Q

what is the endocrine secretions of the liver?

A

glucose

plasma proteins - prothrombin, fibrinogen, albumin, factor 3, LDL

26
Q

what does the liver do in detoxification?

A

liver ditoxifies various drugs and toxins

27
Q

where does IgA uptake in teh liver occur?

A

from blood steam occurs at space of Disse

28
Q

what type of cells are in the mucosa of gallbladder?

A

simple columnar epitheliam and rich vascular LP

29
Q

what is teh sinuses of Rokitansky-Ashoff

A

deep invaginations of epithelium that may extend into the perimuscular CT

30
Q

what are the ducts of Luschka

A

non functional, blind ending ducts in the vacinity of the neck of gall bladder

31
Q

what direction does the flow of blood go?

A

from periphery to central vein

32
Q

what direciton does the flow of bile flow?

A

from hepatocytes to bile canalicui to bile duct in periphery

33
Q

where do you find mV?

A

bile canaliculi and space of Disse

34
Q

what does the classical lobule show?

A

flow of blood

35
Q

what does the portal lobule show?

A

flow of bile

36
Q

what does the rappenport show?

A

flow of blood - connects 2 classical lobules = 2 central v. + 2 portal areas

37
Q

what goes on in zone 1

A

gets the most blood and toxins

38
Q

what goes on in zone 3

A

gest the least blood, less toxin

39
Q

how many nuclei do hepatocytes have?

A

usually 2 - liver can regenerate!

40
Q

what uses sER in hepatocytes?

A

glycogen - syntehsis and degradation

41
Q

what uses rER in hepatocytes?

A

amino acids – protein synthesis – albumin, prothrombin, fibrinogen, lipoprotein

Histology (21 decks)

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