Meds_Guidlines_2

Question 1

antipsychotic with Least effect on lipid profile 🕴️

Answer 1

Aripiprazole 🕴️

Question 2

Max dose for aripiprazole per day

Answer 2

30 mg/day
Aro30

Question 3

Max dose per day for olanzapine

Answer 3

20mg/day
Ola20

Question 4

Max dose perday for clozapine

Answer 4

900 mg/day
900 cluez

Question 5

Minimum effective dose for amisulpride in 1st psychotic episode

Answer 5

300 mg

Question 6

Minimum effective dose for risperidone in relapse of schizophrenia

Answer 6

4 mg

Question 7

Minimum dose of olan for 1st episode of psychosis 🧑‍🌾

Answer 7

5 mg

Question 8

Minimum dose of olan in relapse of schziophrenia

Answer 8

7.5 mg

Question 9

When creatinine phosphokinase monitoring is indicated?

Answer 9

Baseline, if NMS, is suspected (muscle stiffness)

Question 10

What does NMS increase risk of?

Answer 10

Rhabdomyolysis

Question 11

Annual monitring for patients on quetiapine 😇

Answer 11

Thyroid function test 😇

Question 12

Its monitoring required in case of antipsychotics prescription at baseline, 3 months and yearly

Answer 12

Blood lipid

Question 13

Frequency of monitoring blood lipid check in case of antipsychotic prescription

Answer 13

Baseline, 3 months and annually

Question 14

Alternative to olanzapine 🧑‍🌾 & quetiapine 😇 and drug induced orthostatic hypotension 😎

Answer 14

Amisulpride 😎

Question 15

Diagnosis of orthostatic hypotension

Answer 15

A fall in systolic blood pressure >20
a fall in diastolic >10

Question 16

Most commonly caused anticholinergic side effect 🥷

Answer 16

Clozapine 🥷

Question 17

Least association with orthostatic hypotension 🕴️

Answer 17

Aripiprazole 🕴️

Question 18

An antipsychotic that is more likely to cause high prolactine (dyspareunia, amenorrhaea) 🧖‍♂️

Answer 18

Haloperidol 🧖

Question 19

an antipsychotic Most commonly associated with metabolic syndrome 🧑‍🌾

Answer 19

Olanzapine 🧑‍🌾

Question 20

Alternative to risperidone indused sexual dysfunction 🕴️

Answer 20

Aripiprazole 🕴️

Question 21

Most associated with rapid bipolar disorder

Answer 21

Hypothyroidism

Question 22

Most effective drug for treating psychosis associated with parkinson’s 😇🥷

Answer 22

Clozapine 🥷and quetiapine😇

Question 23

1st line of treatment in GAD if psychological approach failed 😁

Answer 23

sertraline (well tolerated) 😁

Question 24

Not to be prescribed in panic disorders

Answer 24

Diazepam (benzodiazepam)

Question 25

What should patients be monitored for in GAD patients under SSRI AND SNRI

Answer 25

suicidal thinking

Question 26

frequency of suicidal thinking monitoring in GAD patients on SSRI AND SNRI

Answer 26

weekly for the 1st month for all<30 year olds

Question 27

1st line treatment in panic disorder

Answer 27

SSRI

Question 28

in case of no response to SSRI in Panic disorder alternative can be...🪕🤓

Answer 28

Imi pramine 🪕 Clomi pramine🤓

Question 29

How long should one wait for SSRI to work before switching to alternatives in panic disorder

Answer 29

12 weeks (NICE)

Question 30

1st line treatment for PTSD

Answer 30

trauma focussed CBT

Question 31

1st line treatment in social anxiety disorder in children (<16)

Answer 31

Group CBT

Question 32

least likely TCA to treat atypical depression🧐

Answer 32

Dosulepin🧐

Question 33

Best for atypical antidepression

Answer 33

MAOIs( ‌‌increase NE,5ht, and da)

Question 34

Alternative to failed non pharma approach in children with Autism with sleep problem 🥱

Answer 34

Melatonin🥱

Question 35

FDA approved 2nd gen antipaychotics for children with austism and aggression and irritability 🕴️🤽‍♂️

Answer 35

Aripiprazole🕴️ Risperidone🤽‍♂️

Question 36

When pharmacological intervention can be considered in irritability associated with autism in children?

Answer 36

When non-pharma and psychological approach failed.

Question 37

Most reliable drug associated with higher risk of autism when used during pregnancy 💘

Answer 37

Valproate 💘

Question 38

Its long term use can cause b12 deficiency

Answer 38

Lanzoprazole ( ppi)

Question 39

Best antipsychotic treatment for mania in children 🕴️

Answer 39

Aripiprazole 🕴️

Question 40

Appropriate medication for children with depression mania 😇

Answer 40

Quetiapine 😇

Question 41

Do not offer it to child bearing age women with bipolar 💘

Answer 41

Valproate 💘

Question 42

Reasonable alternatives to aripiprazole in treating moderate to severe manic episodes in children 🧑‍🌾🤽‍♂️😇

Answer 42

Olan 🧑‍🌾, risperidone🤽‍♂️, quetiapine😇

Question 43

recommended in opiod withdrawal symptoms

Answer 43

lofexidine a2 adrenergic agonist & reduces Noradrenalinr in brain so reduces reslessness and irritability

Question 44

Ultra rapid opiod detox

Answer 44

Naloxone (over 24 hr) under GA. Not recommended by NICE

Question 45

rapid opiod detox

Answer 45

naloxone + naltrexon (1-5 days) only with sedation and only when patient specifically asked for it

Question 46

What is a long-term side effect of clozapine related to gastrointestinal function? 🥷

Answer 46

Gastrointestinal hypomotility ## Footnote Gastrointestinal hypomotility refers to a decrease in the movement of the gastrointestinal tract, leading to potential complications such as constipation.

Question 47

What neurological side effect is associated with clozapine?

Answer 47

Seizures ## Footnote Seizures can occur as a side effect of clozapine, particularly at higher doses.

Question 48

What type of infections are increased as a long-term side effect of clozapine?

Answer 48

Pneumonia and other acute respiratory tract infections ## Footnote Clozapine may increase the risk of respiratory infections due to its immunosuppressive effects.

Question 49

What cardiovascular side effect is associated with clozapine? 🥷

Answer 49

Tachycardia ## Footnote Tachycardia is an increase in heart rate that can occur as a side effect of clozapine treatment.

Question 50

Fill in the blank: A heterogeneous group of side effects from clozapine includes _______ and neutropenia.

Answer 50

diabetes ## Footnote Diabetes can be a metabolic side effect of clozapine, contributing to weight gain and other metabolic issues.

Question 51

What is the cumulative incidence of ileus in clozapine users?

Answer 51

5.3% ## Footnote This indicates a significant risk associated with clozapine use.

Question 52

What is the cumulative incidence of pneumonia in clozapine users?

Answer 52

29.5% ## Footnote This reflects a high adverse side effect burden in patients using clozapine.

Question 53

What is the odds ratio for mortality associated with ileus in clozapine users?

Answer 53

4.5 ## Footnote This suggests that the risk of death is significantly higher for those experiencing ileus.

Question 54

What is the odds ratio for mortality associated with pneumonia in clozapine 🥷 users?

Answer 54

2.8 ## Footnote This indicates an increased risk of death for patients who develop pneumonia while on clozapine.