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ART_MRCPSYCH_B_MENTOR > Meds_Guidlines_2 > Flashcards

Meds_Guidlines_2 Flashcards

1
Q

antipsychotic with Least effect on lipid profile 🕴️

A

Aripiprazole 🕴️

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2
Q

Max dose for aripiprazole per day

A

30 mg/day
Aro30

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3
Q

Max dose per day for olanzapine

A

20mg/day
Ola20

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4
Q

Max dose perday for clozapine

A

900 mg/day
900 cluez

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5
Q

Minimum effective dose for amisulpride in 1st psychotic episode

A

300 mg

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6
Q

Minimum effective dose for risperidone in relapse of schizophrenia

A

4 mg

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7
Q

Minimum dose of olan for 1st episode of psychosis 🧑‍🌾

A

5 mg

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8
Q

Minimum dose of olan in relapse of schziophrenia

A

7.5 mg

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9
Q

When creatinine phosphokinase monitoring is indicated?

A

Baseline, if NMS, is suspected (muscle stiffness)

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10
Q

What does NMS increase risk of?

A

Rhabdomyolysis

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11
Q

Annual monitring for patients on quetiapine 😇

A

Thyroid function test 😇

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12
Q

Its monitoring required in case of antipsychotics prescription at baseline, 3 months and yearly

A

Blood lipid

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13
Q

Frequency of monitoring blood lipid check in case of antipsychotic prescription

A

Baseline, 3 months and annually

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14
Q

Alternative to olanzapine 🧑‍🌾 & quetiapine 😇 and drug induced orthostatic hypotension 😎

A

Amisulpride 😎

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15
Q

Diagnosis of orthostatic hypotension

A

A fall in systolic blood pressure >20
a fall in diastolic >10

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16
Q

Most commonly caused anticholinergic side effect 🥷

A

Clozapine 🥷

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17
Q

Least association with orthostatic hypotension 🕴️

A

Aripiprazole 🕴️

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18
Q

An antipsychotic that is more likely to cause high prolactine (dyspareunia, amenorrhaea) 🧖‍♂️

A

Haloperidol 🧖

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19
Q

an antipsychotic Most commonly associated with metabolic syndrome 🧑‍🌾

A

Olanzapine 🧑‍🌾

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20
Q

Alternative to risperidone indused sexual dysfunction 🕴️

A

Aripiprazole 🕴️

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21
Q

Most associated with rapid bipolar disorder

A

Hypothyroidism

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22
Q

Most effective drug for treating psychosis associated with parkinson’s 😇🥷

A

Clozapine 🥷and quetiapine😇

23
Q

1st line of treatment in GAD if psychological approach failed 😁

A

sertraline (well tolerated) 😁

24
Q

Not to be prescribed in panic disorders

A

Diazepam (benzodiazepam)

25
Q

What should patients be monitored for in GAD patients under SSRI AND SNRI

A

suicidal thinking

26
Q

frequency of suicidal thinking monitoring in GAD patients on SSRI AND SNRI

A

weekly for the 1st month for all<30 year olds

27
Q

1st line treatment in panic disorder

A

SSRI

28
Q

in case of no response to SSRI in Panic disorder alternative can be…🪕🤓

A

Imi pramine 🪕

Clomi pramine🤓

29
Q

How long should one wait for SSRI to work before switching to alternatives in panic disorder

A

12 weeks (NICE)

30
Q

1st line treatment for PTSD

A

trauma focussed CBT

31
Q

1st line treatment in social anxiety disorder in children (<16)

A

Group CBT

32
Q

least likely TCA to treat atypical depression🧐

A

Dosulepin🧐

33
Q

Best for atypical antidepression

A

MAOIs( ‌‌increase NE,5ht, and da)

34
Q

Alternative to failed non pharma approach in children with Autism with sleep problem 🥱

A

Melatonin🥱

35
Q

FDA approved 2nd gen antipaychotics for children with austism and aggression and irritability 🕴️🤽‍♂️

A

Aripiprazole🕴️
Risperidone🤽‍♂️

36
Q

When pharmacological intervention can be considered in irritability associated with autism in children?

A

When non-pharma and psychological approach failed.

37
Q

Most reliable drug associated with higher risk of autism when used during pregnancy 💘

A

Valproate 💘

38
Q

Its long term use can cause b12 deficiency

A

Lanzoprazole ( ppi)

39
Q

Best antipsychotic treatment for mania in children 🕴️

A

Aripiprazole 🕴️

40
Q

Appropriate medication for children with depression mania 😇

A

Quetiapine 😇

41
Q

Do not offer it to child bearing age women with bipolar 💘

A

Valproate 💘

42
Q

Reasonable alternatives to aripiprazole in treating moderate to severe manic episodes in children 🧑‍🌾🤽‍♂️😇

A

Olan 🧑‍🌾, risperidone🤽‍♂️, quetiapine😇

43
Q

recommended in opiod withdrawal symptoms

A

lofexidine

a2 adrenergic agonist & reduces Noradrenalinr in brain so reduces reslessness and irritability

44
Q

Ultra rapid opiod detox

A

Naloxone (over 24 hr) under GA.
Not recommended by NICE

45
Q

rapid opiod detox

A

naloxone + naltrexon (1-5 days) only with sedation and only when patient specifically asked for it

46
Q

What is a long-term side effect of clozapine related to gastrointestinal function? 🥷

A

Gastrointestinal hypomotility

Gastrointestinal hypomotility refers to a decrease in the movement of the gastrointestinal tract, leading to potential complications such as constipation.

47
Q

What neurological side effect is associated with clozapine?

A

Seizures

Seizures can occur as a side effect of clozapine, particularly at higher doses.

48
Q

What type of infections are increased as a long-term side effect of clozapine?

A

Pneumonia and other acute respiratory tract infections

Clozapine may increase the risk of respiratory infections due to its immunosuppressive effects.

49
Q

What cardiovascular side effect is associated with clozapine? 🥷

A

Tachycardia

Tachycardia is an increase in heart rate that can occur as a side effect of clozapine treatment.

50
Q

Fill in the blank: A heterogeneous group of side effects from clozapine includes _______ and neutropenia.

A

diabetes

Diabetes can be a metabolic side effect of clozapine, contributing to weight gain and other metabolic issues.

51
Q

What is the cumulative incidence of ileus in clozapine users?

A

5.3%

This indicates a significant risk associated with clozapine use.

52
Q

What is the cumulative incidence of pneumonia in clozapine users?

A

29.5%

This reflects a high adverse side effect burden in patients using clozapine.

53
Q

What is the odds ratio for mortality associated with ileus in clozapine users?

A

4.5

This suggests that the risk of death is significantly higher for those experiencing ileus.

54
Q

What is the odds ratio for mortality associated with pneumonia in clozapine 🥷 users?

A

2.8

This indicates an increased risk of death for patients who develop pneumonia while on clozapine.

ART_MRCPSYCH_B_MENTOR (38 decks)

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