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MRCPSYCH_Paper B_MENTOR & More_Dr. ART > Meds Guidline - 10 > Flashcards

Meds Guidline - 10 Flashcards

1
Q

max dose for clozapine

A

900 mg/day

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2
Q

max dose for Haloperidol

A

20 mg/day

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3
Q

max dose for Olanzapine

A

20 mg/day

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4
Q

max dose for Quetiapine

A

750 mg for schizophrenia
800 mg for bipolar disorder

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5
Q

max dose for Risperdione

A

16 mg/day

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6
Q

max dose for Amisulpride

A

1200 mg/day

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7
Q

max dose for Aripiprazole

A

30 mg/day

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8
Q

max dose for Flupentixol (depot)

A

400 mg/day

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9
Q

max dose for zuclopenthixol (depot)

A

600 mg/day

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10
Q

haloperidol (depot)

A

300 mg/day

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11
Q

dose in first vs dose in relapse in schizophrenia for chlorpromazine

A

200 mg - 300 mg

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12
Q

dose in first vs dose in relapse in schizophrenia for Haloperidol

A

2 mg - 4 mg

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13
Q

dose in first vs dose in relapse in schizophrenia for Amisulpride

A

300 mg - 400 mg

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14
Q

dose in first vs dose in relapse in schizophrenia for Aripiprazole

A

10 mg - 10 mg

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15
Q

dose in first vs dose in relapse in schizophrenia for Olanzapine

A

5 mg - 7.5 mg

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16
Q

dose in first vs dose in relapse in schizophrenia for Quetiapine

A

150 mg - 300 mg

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17
Q

dose in first vs dose in relapse in schizophrenia for Risperidone

A

2 mg - 4 mg

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18
Q

baseline and annual monitoring in schizophrenia

A

Urea + Electrolytes
FBC
Weight
Glucose
ECG
BP
Prolactive
LFT
Creatine phosphates

19
Q

monitorings that need to be repeated at 3 month for schizophrenia

A

weight and blood lipid

20
Q

monitorings that need to be repeated at 6 months for schizophrenia

A

prolactin and plasma glucose

21
Q

extra monitoring for quetiapine

A

thyroid function test- annually

22
Q

antipsychotics that cause postural hypotention

A

PRO-CloZiQue (close to earth)

Paliperidone
Risperidone
Olanzapine
-
Clozapine
Ziprasidone
Quetiapine

23
Q

antipsychotics to consider if drug-induced postural hypotension is problematic

A

SHATA (Sat up)

Sulpride
Haloperidol
Aripiprazole
Trifluperazine
Amisulpride

24
Q

what class causes drowsiness?

A

histaminergics

25
Q

What class causes postural hypotention

A

antiadrenergics

26
Q

side effects of anticholinergics

A

dry mouth
constipation
urinary retention
blurry vision

27
Q

drugs with no anticholinergic effects (postural hypotension)

A

amisulpride
aripiprazole
asenapine

28
Q

drugs with most anticholinergic effects

A

+++ clozapine
++ most 1st generation

29
Q

drugs with most sedative effects

A

clozapine +++
Olanzapine ++

30
Q

drugs with no sedative effects

A

aripiprazole and amisulpride

31
Q

drugs with most weight gain effects

A

clozpaine & olanzapine

32
Q

drugs with no diabetic effects

A

aripiprazole

33
Q

problem with amisulpride

A

Prolactine +++

34
Q

best antipsychotics for negative symptoms of schizo

A

Clozapine
Amisulpride
Olanzapine

35
Q

1st line antipsychotic for schizoaffective

A

Paliperidone 3 mg and aripiprazole

36
Q

True or false?
There is no first-line antipsychotic drug suitable for all people with psychosis, and (except for clozapine) little meaningful difference in efficacy.

A

True

37
Q

what about antipsychotics cause weight gain?

A

5HT2A and 5HT2C antagonist
D2 & D3 Antagonist
H1 and M3 antagonists
Hyperprolactinemia
Increased serum leptin
Ghrelin

38
Q

GIT enzyme affected by antipsychotic and contribute to weight gain?

A

Leptin
Ghreline

39
Q

antipsychotics with most association with weight gain?

A

CO
clozapine
+
Olanzapine

40
Q

antipsychotic with no weight gain?

A

Amisulpride
aripiprazol
asenapine
Haloperidonl

41
Q

switch to what drugs if weight gain was problematic

A

LAZ

Lurasidone
aripirazole
Ziprasidone

42
Q

what medication can help with clozapine induced weight gain

A

lira glu tide
aripirazole augmentation

43
Q
A

MRCPSYCH_Paper B_MENTOR & More_Dr. ART (69 decks)

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