Meds Guidline - 10 Flashcards by Arteen Ahmed

max dose for clozapine

900 mg/day

How well did you know this?

Not at all

Perfectly

max dose for Haloperidol

20 mg/day

How well did you know this?

Not at all

Perfectly

max dose for Olanzapine

20 mg/day

How well did you know this?

Not at all

Perfectly

max dose for Quetiapine

750 mg for schizophrenia
800 mg for bipolar disorder

How well did you know this?

Not at all

Perfectly

max dose for Risperdione

16 mg/day

How well did you know this?

Not at all

Perfectly

max dose for Amisulpride

1200 mg/day

How well did you know this?

Not at all

Perfectly

max dose for Aripiprazole

30 mg/day

How well did you know this?

Not at all

Perfectly

max dose for Flupentixol (depot)

400 mg/day

How well did you know this?

Not at all

Perfectly

max dose for zuclopenthixol (depot)

600 mg/day

How well did you know this?

Not at all

Perfectly

haloperidol (depot) max

300 mg/day

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for chlorpromazine

200 mg - 300 mg

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for Haloperidol

2 mg - 4 mg

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for Amisulpride

300 mg - 400 mg

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for Aripiprazole

10 mg - 10 mg

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for Olanzapine

5 mg - 7.5 mg

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for Quetiapine

150 mg - 300 mg

How well did you know this?

Not at all

Perfectly

dose in first vs dose in relapse in schizophrenia for Risperidone

2 mg - 4 mg

How well did you know this?

Not at all

Perfectly

baseline and annual monitoring in schizophrenia

Urea + Electrolytes
FBC
Weight
Glucose
ECG
BP
Prolactive
LFT
Creatine phosphates

monitorings that need to be repeated at 3 month for schizophrenia

weight and blood lipid

monitorings that need to be repeated at 6 months for schizophrenia

prolactin and plasma glucose

extra monitoring for quetiapine

thyroid function test- annually

antipsychotics that cause postural hypotention

PRO-CloZiQue (close to earth)

Paliperidone
Risperidone
Olanzapine
-
Clozapine
Ziprasidone
Quetiapine

antipsychotics to consider if drug-induced postural hypotension is problematic

SHATA (Sat up)

Sulpride
Haloperidol
Aripiprazole
Trifluperazine
Amisulpride

what class causes drowsiness?

histaminergics

What class causes postural hypotention

antiadrenergics

side effects of anticholinergics

dry mouth constipation urinary retention blurry vision

drugs with no anticholinergic effects (postural hypotension)

amisulpride aripiprazole asenapine

drugs with most anticholinergic effects

+++ clozapine ++ most 1st generation

drugs with most sedative effects

clozapine +++ Olanzapine ++

drugs with no sedative effects

aripiprazole and amisulpride

drugs with most weight gain effects

clozpaine & olanzapine

drugs with no diabetic effects

aripiprazole

problem with amisulpride

Prolactine +++

best antipsychotics for negative symptoms of schizo

Clozapine Amisulpride Olanzapine

1st line antipsychotic for schizoaffective

Paliperidone 3 mg and aripiprazole

True or false? There is no first-line antipsychotic drug suitable for all people with psychosis, and (except for clozapine) little meaningful difference in efficacy.

True

what about antipsychotics cause weight gain?

5HT2A and 5HT2C antagonist D2 & D3 Antagonist H1 and M3 antagonists Hyperprolactinemia Increased serum leptin Ghrelin

GIT enzyme affected by antipsychotic and contribute to weight gain?

Leptin Ghreline

antipsychotics with most association with weight gain?

CO clozapine + Olanzapine

antipsychotic with no weight gain?

Amisulpride aripiprazol asenapine Haloperidonl

switch to what drugs if weight gain was problematic

LAZ Lurasidone aripirazole Ziprasidone

what medication can help with clozapine induced weight gain

lira glu tide aripirazole augmentation