Meds_Guidlines Flashcards

1
Q

First line treatment in adults adhd

A

Lisdexamfetamine or methylphenidate

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2
Q

2nd line treatment in adults adhd

A

Atomoxetine

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3
Q

3rd line treatment in adult adhd

A

Guanfacine

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4
Q

Alternative Rx to methylphenidate/lisdexamfetamine induced tics in adult adhd?

A

Atomoxetine

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5
Q

Alternative Rx for methyl/disdexamfetamine resistance attention deficiet in adult adhd

A

Atomoxetine

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6
Q

SSRI S.E in baby when taken after 20 weeks of pregnancy

A

Persistent pulmonary hypertension

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7
Q

What needs monitoring in children treated with methylphenidate?

A

Height and weight

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8
Q

Lenght of therapeutic trial of methylphenidate /lisdexamfetamine in children

A

6 weeks

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9
Q

The only antipsychotic licensed in the UK to treat behavioural and psychological symptoms of dementia???

A

Risperidone

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10
Q

NICE guidline: Fist line treatment for adhd in children(pre school)?

A

pArEntal training PrOgrAmmes

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11
Q

When would you prefer atomoxetine to methylphenidate in adhd+conduct disorder in children?

A

When there is a chance of misuse or diversion

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12
Q

Very common s.e of stimulants in adhd

A

Appetite suppression

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13
Q

Stimulant associated with liver toxicity

A

Pemoline

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14
Q

The stimulant that is controlled drug due to abuse and addiction?

A

Methylphenidate

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15
Q

For hallucination associated with delirium tremens(alcohol withdrawal), what psychotropics are preferred?

A

first oral lorazepam, if not applicable or not worked then parenteral lorazepam and Haluperidol

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16
Q

First line opiod detoxifixation drug (NICE)

A

buprenorphine (partial opiod agonist)

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17
Q

What drug that is used to help alcohol abstinence can cause dizziness and abduminal pain?

A

Disulfiram

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18
Q

Mechanism of acamprosate

A

Glutamatergic NMDA antagonist

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19
Q

NICE 1st line treatment to prevent replase in alcohol dependence

A

Naltrexone

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20
Q

NICE recommends it to use to support prevention of replase in alcoholism!!!

A

Nalmefene

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21
Q

Contradicted to be used in myocardial disease or psychosis + alcoholism

A

Disulfiram

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22
Q

Interferes with conversion of aldehyde to acetic acid in alcoholism

A

Disulfiram

23
Q

Not to be used with patients who could be having alcohol withdrawals

A

IV glucose (may precipitate wernick’s encephalopathy)!

24
Q

a hypnotic that is generally avoided in alcohol withdrawal

A

Clomethiazole ( may cause respiratory depression)

25
First line treatment for alcohol withdrawal
Chlordiazepoxide
26
Should be offered to pts with alcohol withdrawal
Thiamine parenteral
27
First line treatment for depression
SSRI
28
NNT for for SSRI in moderate depression
5
29
Assoc. with liver injury when used as antidepressant in elderly
Agomelatine
30
SSRI in elderly increase risk of...
Falls
31
Continue antidepressants in elderly after remission for how long?
12 months (higher chance of relapse)
32
Increases the level of theophylline
Fluvoxamine
33
How long should antidepressant trial last to decide its effectiveness?
4 weeks
34
Causes steven johnson syndrome
Carbamazepine
35
Causes visual impairment
Vigabatrin (assess visual every 3 months)
36
Increases lamotrigine 2 folds
Valproate
37
Causes angle closure glucoma
Topiramate (red, painful eye with vision loss)
38
Causes aggression when used in epilepsy
Levetiracetam Perampanel
39
Can cause cleft palate and floppy baby syndrome in baby
Benzodiazepines
40
Very rare occasion in which bezodiazepine can be used in pregnancy
Extreme anxiety and agitation (when benefits outweigh risks)
41
Contraindicated in patients with uncontrolled epilepsy
Clozapine
42
Most associated with increase in hypertention, hence needs regular monitoring
Clozapine
43
Indicated in schizophrenia +diabetes
Amisulpride 😎
44
Most likely to cause dyslipidemia
Olan
45
What percentage of non compliance is due to forgeting it
10%
46
What scales are used to check compliance
DAI - Drug Attitude Inventory MARS - Medication Adherence Rating scale
47
% of patients with schizo who become non-compliance after 24 months
75%
48
1st line treatment of body dysmorphic disorder
Fluoxetin
49
How long to continue ssri in body dismorphic sybdrome after symtoms reduced
12 month
50
1st line of medical treatment for OCD
ssri (like citalopram)
51
First line treatment for OCD in children
CBT including exposure response prevension
52
How long antidepressant therapy should continue in child ocd
6 months after remission
53
Rx licenced for OCD in young people in UK
fluvoxamine
54
which one is faster in detox buprenorphine or methadone?
buprenorphine