Bipolar - 4 Flashcards

1
Q

Klerman bipolar I

A

Mania with depression

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2
Q

Klerman bipolar type II

A

Hypomania with depression

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3
Q

Klerman bipolar type III

A

Cyclothymic disorder /personality

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4
Q

Klerman bipolar type IV

A

Hypomania or Mania peecipitared by antidepressants

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5
Q

Klerman bipolar type V

A

Depression with a family history of bipolar

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6
Q

Klerman bipolar type VI

A

Mania without depression

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7
Q

Contemporary application of Klerman classification

A

Klerman’s classification is limited; modern psychiatry favours individualized care.

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8
Q

Akiskal classification 1999

A

Bipolar I
Bipolar I 1/2
Bipolar II
Bipolar II 1/2
Bipolar III
Bipolar III 1/2
Biplar IV

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9
Q

Akiska 1999 Bipolar I

A

Full Blown Mania

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10
Q

Akiska 1999 Bipolar I 1/2

A

Depression with protracted hypomania

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11
Q

Akiska 1999 Bipolar II

A

depression with hypomania

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12
Q

Akiska 1999 Bipolar II 1/2

A

Cyclothymic depressions

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13
Q

Akiska 1999 Bipolar III

A

antidepressant associated hyomania

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14
Q

Akiska 1999 Bipolar III 1/2

A

Bipolarity unmasked/masked by substance abuse

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15
Q

Akiska 1999 Bipolar IV

A

Hyperthymic depression

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16
Q

Main differences between bipolar and borderline personality disorders

A

-Psychomotor activation in BD
-Self destructive behaviours in BPD
-Hx of sexual trauma in BPD
-Characteristic features of BPD
-Genetic

17
Q

What are psychomotor activations in BD

A

-Decrease need for sleep
-Higher energy
-Increased goal-directed activities
- Pressured speech

18
Q

Prevalence of self-disctructive cutting behaviours in Borderline vs Bipolar

A

Borderline ===>50-80%
Bipolar ===> Very Uncommon

19
Q

Hx of sexual trauma in Borderline PD VS bipolar

A

Borderline 40-70%
Bipolar 20-40%

20
Q

Hx of sexual trauma in general population

A

13-17% females
2.5-5% in males

21
Q

Borderline characteristic that rarely seen in bipolar

A
  • Abandonment
  • Identity disturbance
  • Recurrent suicidal or self mutilating behaviours
  • Dissociative symptoms
22
Q

Heritability of bipolar

A

80-90%

23
Q

Overal risk of postpartum biplar relapse

A

37%

24
Q

Postpartum replace % on prophylactic bipolar vs off prophylactic bipolar

A

23% vs 66%

25
Q

Bipolar medications that should be stoped in pregnant bipolar patients

A

Valproate
Lithium
Carbamazepine
Lamotrigine

26
Q

What do NICE and Maudsley offer for pregnant patient with bipolar

A

Antipsychotics

27
Q

What is a pregnant patient with bipolar is on lithium?

A

Stop slowly over 4 weeks to avoid relapse
Then start antipsychotics

28
Q

What if

a patient with bipolar gets pregnant and cannot come off lithium?

A

Check the level of lithium every 4 weeks until week 36, then every week

29
Q

What happens to lithium level in pregnancy

A

Drops

30
Q

How to manage a bipolar pregnant women with mild depression

A

-Self help (computerised cbt)
-Brief psychological interventions
-Antidepressants

31
Q

Average brief psychological intervention

A

5-8 sessions

32
Q

Pregnant patient develops actue mania, Rx is

A

Antipsychotic

33
Q

Moderate to severe depression in pregnant women with bipolar

A

CBT ====>Moderate
CBT + Medication ===> severe