Med_Guidlines_7

Question 1

Treatment option for post stroke pathological emotional liability (crying)

Answer 1

Amitriptyline

Question 2

Rx of psychotic depression (NICE and Maudsley)

Answer 2

A TCA (amitriptiline) and antipsychotic (Olan or quetiapine)

Question 3

TCA resistant (not tolerated) psychotic depression [NICE]

Answer 3

SSRI WITH antipsychotics

Question 4

the antipsychotic most associated with high THS levels?

Answer 4

Quetiapine

Question 5

An antipsychotic that may disturbe liver enzymes

Answer 5

Olanzapine

Question 6

Clozapine causes which enzyme to raise?

Answer 6

ALP

Question 7

Does clozapine induced high ALP require dose adjustment?

Answer 7

Not often
Only if there are sympoms like Nausea, weakness and abd discomfort

Question 8

Mood stabilizer mostly associated with liver toxicity

Answer 8

Valproate

Question 9

A psychotropic that causes a drop in ALT and AST enzymes

Answer 9

Vigabatrin

Question 10

Antidepressant that should be avoided in depression + epilepsy

Answer 10

Bupropion
Amitriptyline

Question 11

Most appropreiate antidepressant for depression in epilepsy

Answer 11

SSRIs like Citalopram and sertralin
Mirtazapine

Question 12

Highly pro convulsive antidepressant

Answer 12

TCAs

Question 13

Antipsychotic with highest impact on siezure

Answer 13

Clozapine

Question 14

Antipsychotic with low impact on siezure

Answer 14

Haloperidol

Question 15

Used to manage dementia in Parkinson’s

Answer 15

Ache I: donepezil, rivastigmine galantamine (supported by RCT and metaanalysisi

Question 16

Drug used to treat hypersalivation from clozapine

Answer 16

Hyoscin hydrobromide

Question 17

Antipsychotic that elevates risk of cardiac arrest?

Answer 17

Thoridazine & droperidol

Question 18

SSRI most likey to cause QTc prolongation

Answer 18

Citalopram

Question 19

QT prolongation induced drugs

Answer 19

Erythromycin
Antimalaria
Citalopram
holoperidol

Question 20

Mental or electrolye condition that are associated with QTc prolongation

Answer 20

Anorexia nervosa
hypokalaemia
hypomagnesaemia
hypocalcemia

Question 21

Tachy or brady cardia increases risk of qtc prolongation

Answer 21

Brady

Question 22

What to do if quetiapine caused QTc prolongation

Answer 22

Stop the Que
switch to Aripiprazole
refer to cardiologist

Question 23

an antipsychotic with minimal effect on QTc

Answer 23

Aripiprazole

Question 24

In a non_pharma resisted Restless leg syndrome which treatment can help

Answer 24

Gabapentin (1st line NICE)
Low potency opiod like codeine

Question 25

Approve antipsychotic for adolescent schizophrenia

Answer 25

Risperidone or aripiprazole (2mg) (+ family intervention with individual CBT)

Question 26

daily max dose of olan in 12-17 (BNF) in schizophrenia

Answer 26

20 mg

Question 27

Is rapid neuroleptisation allowed in children with schizophrenia?

Answer 27

Nope! (NICE) no loading dose

Question 28

1 most affective antipsychotic for prominent negative symptoms schizo

Answer 28

Amisulpride

Question 29

In PTSD when patient did not respond to SSRI, what is the next solution?

Answer 29

Venlafaxine (NICE)

Question 30

recommended antidepressant in **elderly** patient depressed with broken hip on **beta blockers** for AF and inuprofen for osteoarthritis

Answer 30

Mirtazapine Good for sleep regulation, appetite boost and cardio safe

Question 31

1st line treatment for post MI depression

Answer 31

SSRI like sertraline

Question 32

Non-addictive choise for opiod detox

Answer 32

Lofexidine

Question 33

2nd line of treatment after ssri in ptsd

Answer 33

Venlafaxine

Question 34

Med indicated to reduce nightmares in PTSD if other approaches failed

Answer 34

prozasin (blocks a1 adrenergics and reduce hyperarousal)

Question 35

Not recommended in PTSD

Answer 35

amitriptyline

Question 36

Antidepressant for a patient on tamoxifen

Answer 36

Venlafaxine and Citalopram (NO CYP2D6 Inhibitor like fluoxetine)

Question 37

Medication that causes swallowing difficult in learning disability

Answer 37

Clonazepam

Question 38

Drug licenced for tardive dyskinesia

Answer 38

Tetrabenzine

Question 39

Alternative to haloperidol when patien develops Tardive dyskinesia

Answer 39

Quetiapine

Question 40

TARDIVE d. is due to

Answer 40

Hypersensitiviy of D2

Question 41

epilepsy med that is associated with weight loss

Answer 41

topiramate

Question 42

most appr. Rx for 10 y.o with tourette's who did not respond to to comprehensive behavioural intervention for Tics (CBIT)

Answer 42

Clonidine (alpha 2 adrenergic agonist

Question 43

Drug licenced for acute psychmotor agitation in psychosis

Answer 43

Oral olan 10 mg

Question 44

Rapid tranquilisation

Answer 44

Inhaled loxapine

Question 45

Contraind. for loxapine

Answer 45

Asthma & COPD

Question 46

combined with IM haloperidol for rapid tranquilisation

Answer 46

promethazine

Question 47

Conventional antipsychotic licensed for depression (BNF)

Answer 47

Flupentixol

Question 48

Mechanism of action flupentixol

Answer 48

Strong D1 and D2 antagonist weak 5-HT2A antagonist

Question 49

Dose of Flupentixol as antidepressant

Answer 49

0.5-3 mg/day

Question 50

When IM Flupentixol is an option for depression? (Maudsley)

Answer 50

if the alternative to the oral route is needed