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ART_MRCPSYCH_B_MENTOR > Med_Guidlines_7 > Flashcards

Med_Guidlines_7 Flashcards

1
Q

Treatment option for post stroke pathological emotional liability (crying)

A

Amitriptyline

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2
Q

Rx of psychotic depression (NICE and Maudsley)

A

A TCA (amitriptiline) and antipsychotic (Olan or quetiapine)

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3
Q

TCA resistant (not tolerated) psychotic depression [NICE]

A

SSRI WITH antipsychotics

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4
Q

the antipsychotic most associated with high THS levels?

A

Quetiapine

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5
Q

An antipsychotic that may disturbe liver enzymes

A

Olanzapine

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6
Q

Clozapine causes which enzyme to raise?

A

ALP

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7
Q

Does clozapine induced high ALP require dose adjustment?

A

Not often
Only if there are sympoms like Nausea, weakness and abd discomfort

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8
Q

Mood stabilizer mostly associated with liver toxicity

A

Valproate

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9
Q

A psychotropic that causes a drop in ALT and AST enzymes

A

Vigabatrin

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10
Q

Antidepressant that should be avoided in depression + epilepsy

A

Bupropion
Amitriptyline

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11
Q

Most appropreiate antidepressant for depression in epilepsy

A

SSRIs like Citalopram and sertralin
Mirtazapine

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12
Q

Highly pro convulsive antidepressant

A

TCAs

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13
Q

Antipsychotic with highest impact on siezure

A

Clozapine

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14
Q

Antipsychotic with low impact on siezure

A

Haloperidol

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15
Q

Used to manage dementia in Parkinson’s

A

Ache I: donepezil, rivastigmine galantamine (supported by RCT and metaanalysisi

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16
Q

Drug used to treat hypersalivation from clozapine

A

Hyoscin hydrobromide

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17
Q

Antipsychotic that elevates risk of cardiac arrest?

A

Thoridazine & droperidol

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18
Q

SSRI most likey to cause QTc prolongation

A

Citalopram

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19
Q

QT prolongation induced drugs

A

Erythromycin
Antimalaria
Citalopram
holoperidol

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20
Q

Mental or electrolye condition that are associated with QTc prolongation

A

Anorexia nervosa
hypokalaemia
hypomagnesaemia
hypocalcemia

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21
Q

Tachy or brady cardia increases risk of qtc prolongation

A

Brady

22
Q

What to do if quetiapine caused QTc prolongation

A

Stop the Que
switch to Aripiprazole
refer to cardiologist

23
Q

an antipsychotic with minimal effect on QTc

A

Aripiprazole

24
Q

In a non_pharma resisted Restless leg syndrome which treatment can help

A

Gabapentin (1st line NICE)
Low potency opiod like codeine

25
Q

Approve antipsychotic for adolescent schizophrenia

A

Risperidone or aripiprazole (2mg) (+ family intervention with individual CBT)

26
Q

daily max dose of olan in 12-17 (BNF) in schizophrenia

A

20 mg

27
Q

Is rapid neuroleptisation allowed in children with schizophrenia?

A

Nope! (NICE)

no loading dose

28
Q

1 most affective antipsychotic for prominent negative symptoms schizo

A

Amisulpride

29
Q

In PTSD when patient did not respond to SSRI, what is the next solution?

A

Venlafaxine (NICE)

30
Q

recommended antidepressant in elderly patient depressed with broken hip on beta blockers for AF and inuprofen for osteoarthritis

A

Mirtazapine

Good for sleep regulation, appetite boost and cardio safe

31
Q

1st line treatment for post MI depression

A

SSRI like sertraline

32
Q

Non-addictive choise for opiod detox

A

Lofexidine

33
Q

2nd line of treatment after ssri in ptsd

A

Venlafaxine

34
Q

Med indicated to reduce nightmares in PTSD if other approaches failed

A

prozasin (blocks a1 adrenergics and reduce hyperarousal)

35
Q

Not recommended in PTSD

A

amitriptyline

36
Q

Antidepressant for a patient on tamoxifen

A

Venlafaxine and Citalopram (NO CYP2D6 Inhibitor like fluoxetine)

37
Q

Medication that causes swallowing difficult in learning disability

A

Clonazepam

38
Q

Drug licenced for tardive dyskinesia

A

Tetrabenzine

39
Q

Alternative to haloperidol when patien develops Tardive dyskinesia

A

Quetiapine

40
Q

TARDIVE d. is due to

A

Hypersensitiviy of D2

41
Q

epilepsy med that is associated with weight loss

A

topiramate

42
Q

most appr. Rx for 10 y.o with tourette’s who did not respond to to comprehensive behavioural intervention for Tics (CBIT)

A

Clonidine (alpha 2 adrenergic agonist

43
Q

Drug licenced for acute psychmotor agitation in psychosis

A

Oral olan 10 mg

44
Q

Rapid tranquilisation

A

Inhaled loxapine

45
Q

Contraind. for loxapine

A

Asthma & COPD

46
Q

combined with IM haloperidol for rapid tranquilisation

A

promethazine

47
Q

Conventional antipsychotic licensed for depression (BNF)

A

Flupentixol

48
Q

Mechanism of action flupentixol

A

Strong D1 and D2 antagonist
weak 5-HT2A antagonist

49
Q

Dose of Flupentixol as antidepressant

A

0.5-3 mg/day

50
Q

When IM Flupentixol is an option for depression? (Maudsley)

A

if the alternative to the oral route is needed

51
Q
A

ART_MRCPSYCH_B_MENTOR (38 decks)

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