Medical SLP - Exam 1 Flashcards
What are the steps in cell division?
meiosis, haploids, 24 hours pass, mitosis (segmentation and cell differentiation)
Meiosis
- Chromosomes
- Zygote
special cellular division that creates the egg and sperm in the first place
- Ch: 46 total (2 sex)
- Zy: fertilized egg
Mitosis
cell division
Segmentation
(part of mitosis; also called cleavage) cell divides and creates another cell just like it.
Blastomere: cells within Morula
Morula: group of blastomeres in one cell after 72 hours
Cell Differentiation
6th or 8th day; mother cell has a baby cell that is different.
- Trophoblast
- Gastrulation
- Embryonic Disc
Trophoblast
Lining, surrounds the inner mass, not a part of the embryo. Becomes placenta and umbilical cord.
Gastrulation
9th and 12th day; inner cell mass turns itself inside out.
no success in this = miscarriage
Embryonic Disc
3 layers - organs are a combination of these layers
1) Ectoderm: outside - skin, hair, teeth, CNS&PNS
2) Mesoderm: middle - structural (bone, muscle, cartilage, tendons, blood vessels, connective tissue).
3) Endoderm: inner - lining of digestive tract and body cavities, inside tissue.
What governs all cell functions?
Genes, which are made up on DNA
DNA
smallest structure in genetic material, double strand in a double helix whose spine is made of deoxyribose. Contains Nucleotide pairs.
Nucleotide Pairs
instructions for cellular behaviors
Guanine, Cytosince, Adenine, Thymine
Monosomy
loss of one copy of a chromosome; the presence of a single copy of a chromosome
Triosomy
the gain of one extra copy of a chromosome for a total of 3 chromosomes
Deletion
when part of a chromosome becomes separated and lost
Inversion
occurs when a portion of a chromosome is turned 180 degrees from its usual orientation
Translocations
the result of a transfer of genetic material between 2 or more chromosomes
- Variable expression
- Genotype
- Phenotype
- Incomplete penetration
Variable expression (translocations)
severity levels, functional levels
Incomplete Penetration (translocations)
have a genetic disorder but no symptoms
Common syndromes associated with cleft
down syndrome
Merging
growth process where a structure gets bigger. (how it grows/ strengthens/ widens)
Fusion
process that develops the palate. When 2 separate structures grow towards each other and fuse together.
Sequence
process of genetic formation. Because this thing happened, this thing happened.
Pierre Robin
a sequence causing cleft palate (embryo is hyper-flexed in uterus, neck causes the mandible to push up against the chest causing it not to grow. No place for tongue to go, goes up where the palate is suppose to be forming)