M3: The Adrenal Glands Flashcards
This secretes glucocortoids, mineralocorticoids, and small amounts of sex hormones. This is regulated by hormones from pituitary and hypothalamus.
Outer Cortex/ Adrenal Cortex
This secretes epinephrine and norepinephrine
Adrenal Medulla
Location of adrenal glands
At the top of kidneys
Outermost layer and protective covering of the adrenal glands
Capsule
A group of hormones involved in glucose metabolism, the immune system, and stress regulation produced by the adrenal cortex.
Glucocorticoids
The release of glucocorticoid hormones from the adrenal cortex.
Glucocorticoids secretion
Responsible for secreting cortisol
Adrenal Cortex
- Promotes the use of fats and proteins as energy sources
- Causes muscle tissues to break down proteins to amino acids, which the liver can convert to glucose
Cortisol
- Has anti-inflammatory properties by suppressing the immune system and reducing swelling
- Having a high level of this can cause suppression of immune system
Cortisol
This is released from the pituitary gland when cortisol is low, to signal the adrenal glands into producing more cortisol.
Adrenocorticotropic hormone (ACTH)
This is released by the hypothalamus when cortisol levels drop, causing ACTH to be produced from the anterior pituitary gland.
Cortisol-releasing hormone (CRH)
- This is affected by physical injury or emotional stress, that makes a marked increase in cortisol
- Increased when stress triggers the hypothalamic pituitary adrenal (HPA) acix
Cortisol secretion
DISEASES OF ADRENAL GLANDS:
Resulted from excess cortisol due to adrenal cortex hypersecretion which leads to:
- Muscle breakdown
- Fat redistribution (moon face, fat on the back of the neck)
- High blood sugar
- Weak bones
- Hypertension
- Mood swings
Cushing’s Syndrome
DISEASES OF ADRENAL GLANDS:
Caused by low glucocorticoid and aldosterone levels, often due to an autoimmune condition.
Symptoms include:
- Mental slowness
- Anorexia
- Weight loss
- Skin bronzing
An example of someone with this condition is former US president JFK.
Addison’s Disease