M3. Nomenclature & classification of Enzymes

Question 1

Ezymes are named based on its?

three

Answer 1

1. function
2. type of reaction
3. substrate identity

Question 2

enzymes ends in the suffix?

w/ the exception for DIGESTIVE ENZYMES

Answer 2

-ase

Question 3

the prefix of an enzyme is based on the?

Answer 3

type of reaction.

ex.
oxidase: oxidation reaction
hydrolase: hydrolysis reaction

Question 4

• substance acted upon by the enzyme.
• REACTANT in an enzyme.

Answer 4

Substrate

Question 5

1. the substrate for amylase
2. the substrate for maltase

Answer 5

1. starch
2. maltose

Question 6

classified and named the enzymes according to the type of chemical reaction they catalyzed.

Answer 6

International Union of Biochemistry

Question 7

6 classification of enzymes?

Answer 7

1. oxidoreductases
2. transferases
3. hydrolases
4. lyases
5. isomerases
6. ligases

Question 8

• oxidation & reduction occurs simultaneously
• the transfer of H & O atoms/electrons from one substance to another.

examples?

Answer 8

Oxidoreductases

1. oxidases
2. dehydrogenases
3. reducatases

Question 9

Oxidoreductases:

1. Number of C to O bonds increases (oxidation), the number of C to H bonds ____ (reduction)
2. Number of C to H bonds decreases, the number of C to O bonds ____.

to conclude, we can say that OXIDATION & REDUCTION are ____ to each other.

Answer 9

1. decreases
2. increases

INVERSELY PROPORTIONAL

Question 10

1. for transfer of specific functional group
2. examples?

groups may also be?

Answer 10

1. Transferases
2. Examples:
   - kinases
   - transaminases
   - phosphate group transfer
   - amino group transfer

-methy group
-acyl group

Question 11

1. formation of two products from a substrate by hydrolysis
2. examples?

Answer 11

1. Hydrolases
2. Examples?
   - lipase
   - amylase
   - peptidase

Question 12

• non-hydrolytic addition or removal of groups from substrates.
• C-C, C-N, C-O, C-S can be cleaved.

Examples?

Answer 12

Lyases

1. decarboxylase
2. hydratase
3. dehydratese

Question 13

1. removal of CARBOXYL GROUP
2. addition of water
3. removal of water

Answer 13

1. decarboxylase
2. hydratase
3. dehydratase

Question 14

1. enzyme that causes intramolecular rearrangement
2. examples?

Answer 14

1. isomerases
2. examples:
   - isomerase
   - mutase

Question 15

1. BOND FORMATION of two substrate molecules with a simultaneous breakdown of ATP.
2. examples?

Answer 15

1. Ligases
2. examples:
   - synthetase
   - carboxylase