M3. Enzyme inhibition

Question 1

slows or stops the normal catalytic function

Answer 1

Enzyme Inhibitor

Question 2

3 types of Enzyme inhibitors?

Answer 2

1. reversible competitive inhibition
2. reversible non-competitive inhibition
3. irreversible inhibition

Question 3

• can be restored.
• molecule that sufficiently resembles an enzyme substrate inshape and charge distribution
• compete with the substrate for occupancy of the enzyme active site

Answer 3

reversible competitive inhibition

Question 4

• cannot be restored
• causes permanent change in the structure
• it binds against the allosteric site

Answer 4

reversible non-competitive inhibition

Question 5

molecule that inactivates enzymes by forming a STRONG COVALENT BOND to an AMINO ACID’S SIDE CHAIN GROUP.

Answer 5

irreversible inhibition

Question 6

blocks the cyclooxygenase pathway, an enzyme needed for the synthesis of prostaglandins.

Answer 6

Aspirin