M2. Nucleic Acids Flashcards

1
Q
  • found in the nucleus
  • acidic
  • a polymer in which the monomer units are nucleotides.
A

NUCLEIC ACIDS

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2
Q

Two Types of Nucleic Acids (Polymers):

A
  1. DNA - Deoxyribonucleic Acid
  2. RNA - Ribonucleic Acid
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3
Q
  • Found within the cell nucleus and mitochondria
  • Storage and transfer of genetic information
  • Passed from one cell to other during cell division
A

DNA

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4
Q
  • Occurs in ALL parts of cell
  • Primary function is to synthesize the proteins
A

RNA

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5
Q

3 components of Nucleotides:

PPH

A
  1. Pentose Sugar: Monosaccharide
  2. Phosphate group (PO4^-3)
  3. Heterocyclic Base
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6
Q
  • RIBOSE in RNA
  • 2-DEOXYRIBOSE in DNA

  1. differ in the identity of the sugar unit in their nucleotides.
  2. a ____ present on carbon 2’ in ribose
  3. a ____ in 2-deoxyribose
A

[Nucleotides] PENTOSE SUGAR

  1. RNA and DNA
  2. —OH group
  3. —H atom
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7
Q
  1. derived from phosphoric acid (H3PO4)
  2. Under cellular pH conditions, the ____ is fully dissociated to give a hydrogen phosphate ion (HPO4^2-)
A

[Nucleotides] PHOSPHATE GROUP
1. Phosphate
2. Phosphoric acid

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8
Q

there are a total of 5 Nitrogenous-containing heterocyclic bases, and they are?

A
  1. adenine
  2. guanine
  3. cytosine
  4. thymine
  5. uracil
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9
Q

2 types of the Nitrogen-containing heterocyclic bases?

A
  1. Pyrimidine
  2. Purine
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10
Q

Three types PYRIMIDINE derivatives:

TCU - tissue rgiajn

A
  1. thymine
  2. cytosine
  3. uracil
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11
Q

Two types PURINE derivatives:

A
  1. adenine
  2. guanine
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12
Q

these nitrogenous bases are found both in DNA and RNA:

A
  1. adenine
  2. guanine
  3. cytosine
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13
Q

this nitrogenous bases can be found only in RNA.

A

uracil

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14
Q

this nitrogenous bases can be found only in DNA.

A

thymine

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15
Q

the formation of nucleotide are from?

A
  1. sugar
  2. base
  3. phosphate
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16
Q
  1. Phosphate attached to ____.
  2. Base is attached to ____.
A
  1. C-5’
  2. C-1’ position of pentose
17
Q

Primary Structures:

are

A
  1. RNA
  2. DNA
18
Q
  • a nucleotide polymer
  • its monomer units contains:
    1. ribose
    2. phosphate group
    3. one of the heterocyclic bases (A,G,C,U)
A

RNA

19
Q
  • a nucleotide polymer as well
  • its monomer units contains:
    1. deoxyribose
    2. phosphate group
    3. one of the heterocyclic bases (A,G,C,T)
A

DNA

20
Q

Differences between RNA and DNA Molecules:

The sugar unit in the backbone of:
1. RNA?
2. DNA?

A
  1. ribose
  2. deoxyribose
21
Q

Differences between RNA and DNA Molecules:

The base found in:
1. RNA?
2. DNA?

A
  1. uracil
  2. thymine
22
Q

Differences between RNA and DNA Molecules:

Number of their stranded molecule:
1. RNA?
2. DNA?

Ewan ko kung paano i-explain! Basta yung stranded chuchu XD

A
  1. single-stranded molecule
  2. double-stranded molecule [double helix]
23
Q

Differences between RNA and DNA Molecules:

RNA molecules are much ____ than DNA molecules
[ranging from 75 nucleotides to a few thousand nucleotides]

A

smaller

24
Q

PRIMARY STRUCTURE

Primary structure is due to changes in the ____.

Sequence of nucleotides in DNA or RNA

A

[nitrogenous] bases

25
Q

PRIMARY STRUCTURE

____ bond at 3’ and 5’ position.

A

Phosphodiester

26
Q

PRIMARY STRUCTURE

1) 5’ end has ____.
2) 3’ end has a ____.
3) Sequence of bases read from ____.

A
  1. free phosphate
  2. free OH group
  3. 5’ to 3’
27
Q

Backbone of Nucleic Acids?

A

Phosphate Sugar

28
Q

Backbone of Proteins?

A

Peptide Bonds