M2.6. Translation. Flashcards

1
Q

a process in which mRNA codons are deciphered to synthesize a protein molecule

A

Translation

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2
Q
  • an rRNA–protein complex
  • serves as the site of protein synthesis
A

Ribosome

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3
Q

Ribosomes contain:

A
  • 4 rRNA molecules
  • 80 proteins packed into two rRNA-protein subunits (one small and one large)
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4
Q

Ribosomes are?
1. ____ % rRNA
2. ____ % protein by mass

A
  1. 65%
  2. 35%
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5
Q

A ribosome’s active site -

I don’t get this part :<

A

Large subunit

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6
Q

a RNA catalyst

A

Ribosome

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7
Q

binds to the small subunit of the ribosome.

A

mRNA

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8
Q

Five Steps of Translation Process?

AIE TP

A
  1. Activation of tRNA
  2. Initiation of protein synthesis
  3. Elongation
  4. Termination
  5. Post-translational processing
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9
Q

addition of specific amino acids to the 3’-OH group of tRNA.

A

Activation of tRNA

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10
Q

Begins with binding of mRNA to small ribosomal subunit such that its first codon (initiating codon AUG) occupies a site called the P site (peptidyl site)

A

Initiation of protein synthesis

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11
Q

Adjacent to the P site in an mRNA–ribosome complex is A site (aminoacyl site) and the next tRNA with the appropriate anticodon binds to it.

A

Elongation

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12
Q

The polypeptide continues to grow via translocation until all necessary amino acids are in place and bonded to each other.

A

Termination

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13
Q

gives the protein the final form it needs to be fully functional

A

Post-translational processing

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14
Q

the first codon [initiating codon AUG] occupies a site called?

what amino acid is present in AUG?

A

P site/ Peptidyl site

methionine

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15
Q

P site is adjacent to?

A

A site/ Aminoacyl site

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