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DTPS > Loratadine > Flashcards

Loratadine Flashcards

1
Q

Drug class

A

Antihistamine

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2
Q

Pharmacology

A

Long-acting, second generation peripheral histamine H1-receptor antagonistic used to treat allergies

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3
Q

Metabolism

A

Absorbed in the gastrointestinal tract with a rapid first-pass hepatic metabolism

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4
Q

Indications

A

Symptomatic urticaria (without evidence of anaphylaxis)

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5
Q

Contraindications

A
  • Allergy and/or adverse drug reaction

* Anaphylaxis

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6
Q

Precautions

A
  • Severe hepatic impairment

* Older pts - > risk of sedation & anticholinergic effects

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7
Q

Side effects

A
  • Drowsiness
  • Fatigue
  • Headache
  • Nausea
  • Dry mouth
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8
Q

Presentation

A

10mg tablet

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9
Q

Onset

Duration

A

~ 1-2hrs

~ 24hrs

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10
Q

Adult Dosages

A

PO 10mg, single dose only

* not within 24hrs or previous antihistamine

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11
Q

Paediatric dosages

A

≥ 8yrs 10mg, single dose only

* not to be admin within 24hrs of previous antihistamine

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DTPS (47 decks)

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