Droperidol

Question 1

Drug class

Answer 1

Antipsychotic

Question 2

Pharmacology

Answer 2

Antipsychotic drug from the butyrophenone group that produces sedation

Question 3

Metabolism

Answer 3

Hepatic metabolism with biliary/renal excretion as inactive metabolites

Question 4

Indications

Answer 4

Acute behavioural disturbances (ABDs)

With SAT score ≥ 2

Question 5

Contraindications

Answer 5

• Allergy and/or adverse drug reaction
• Parkinson’s disease
• Previous dystonic reaction to droperidol
• Pts <8yrs

Question 6

Precautions

Answer 6

Concomitant use of CNS depressants

Question 7

Side effects

Answer 7

Extrapyramidal effects e.g dystonic reactions

Question 8

Presentation

Answer 8

10mg/2ml vial

Question 9

Onset

Duration

Answer 9

IV/IM 5-15min

Duration IV/IM 4-6hrs

Question 10

Routes of administration

Answer 10

IM / IV

Question 11

Adult dosages

Answer 11

*Must consult ≥ 65 OR 13-15yrs

IM & IV

≥65yrs - 5mg
Repeated once @ 15min
Total max dose 10mg

16yrs-64yrs - 10mg
Repeated once @ 15min
Total max dose 20mg

13-15yrs - 0.1-0.2mg/kg
Single max dose 10mg
Repeated once @ 15min
Total max dose 20mg

Question 12

Paediatric dosages

Answer 12

• Must consult in ALL situations

IM & IV

8-12yrs 0.1-0.2mg/kg
Single max dose 10mg
Repeated at 15min
Total max dose 20mg