LO8 Flashcards
cellular respiration is ________ and ________
catabolic and exergonic
glucose is ______ in aerobic respiration
oxidized
the free energy released during catabolism powers
ATP synthase
oxygens acts as an electron ________
acceptor
summary equation of aerobic respiration
C6H12O6 + 6O2 –> 6CO2 + 6H2O + ATP
H2O is formed when O2 accepts H atoms from _____
glucose
oxygen is _____ in aerobic respiration
reduced
aerobic respiration produces _____ ATP molecules per glucose molecule
36-38`
Four stages of aerobic respiration
glycolysis, formation of acA, citric acid cycle, and electron transport and chemiosmosis
in eukaryotes glycolysis occurs in the ________ and is ________
cytosol; anaerobic
in eukaryotes all other stages of aerobic respiration occur in the _______ and are _________
mitochondria; aerobic
Eukaryotes: formation of acetyl CoA and citric acid cycle occur in the ______ of the mitochondria
matrix`
Eukaryotes: The electron transport train and chemiosmosis occur on the ______ of the mitochondria
cristae
definition: the coupling of the diffusion of H+ ions across a membrane to the phosphorylation of ADP to ATP
chemiosmosis
Prokaryotes: glycolysis, formation of acetyl CoA and citric acid cycle occur in the _______
cytosol
Prokaryotes: ETC and chemiosmosis always require a membrane and occur on the ________________
plasma membrane
glycolysis splits glucose into ___________
2 pyruvates
pyruvate is also written as
G3P
initial reactions involved in glucose catabolism are actually endergonic and must be coupled with
the hydrolysis of ATP
____ ATP molecules are are used to phosphorylate glucose in two seperate reactions
2
phase 1 of glycolysis summary equation
glucose + 2 ATP –> 2 G3P + 2ADP
in the second phase of glycolysis G3P is converted to
pyruvate
___ total ATP are produced during glycolysis by substrate level phosphoraylation
4
definition: when a phosphate group is transferred to ADP from an intermediate in the pathway forming ATP
substrate level phosphorylation
phase 2 of glycolysis summary equation
2 G3P + 2 NAD+ + 4 ADP –> 2 Pyruvate + 2 NADH + 4 ATP
formation of acetyl CoA converts ________ to _________
pyruvate to acetyl CoA
each 3-C pyruvate goes through decarboxylation and becomes
2-C acetyl molecule
_____ is produced as each 2-C acetyl molecules is oxidized
NADH
each acetyl molecule attaches to _____________ forming acetyl CoA
coenzyme A
definition: a cofactor needed to transfer each acetyl group to the citric acid cycle
Coenzyme A
Equation: formation of acetyl CoA
2 pyruvate + 2 NAD+ + 2 CoA –> 2 acetyl CoA + 2 NADH + 2 CO2
citric acid cycle ________ acetyl groups
oxidized
citric acid cycle starts with ____________ releasing its 2-C acetyl group
coenzyme A
The ________ binds with a _______ to from 6-C citrate
2-C acetyl; 4-C oxaloacetate
citric acid cycles _____ per glucose
twiice
Citric Acid Cycle: glucose is completely ________
oxidized
In one citrate cycles what reactions occur
- carboxyl group is removed
- 3 NADH and 1 FADH2 are formed
3.1 ATP is produced by substate-level phosphorylation - 4-C oxaloacetate is regenerated
ETC made up of _____ that can exist in an oxidized or reduced state
membrane proteins
ETC Steps
- Complex 1 accepts e- from NADH and Complex II accepts e- from FADH2
- Complex 1 and II transfer electrons to Complex III via mobile electron carrier
3.Complex 3 transfers electrons Complex IV via a mobile electron carrier - complex IV passes low energy electrons to O2
mobile electron carrier that transfers complex I and II
coenzyme Q
mobile electron carrier that transfers from Complex III to IV
cytochrome c
O2 is the _________ of aerobic respiration
final electron acceptor
ETC makes the ___________
proton concentration gradient
electron flow during the ETC is couples to ____________
proton pumping
high energy electrons of NADH and FADH2 ___________ as they are passed through the complexes of the ETC
lose free energy
ETC Is an ________ process
exergonic
the exergonic process of ETC is used to pump ____________ across the cristae from the matrix –> the intermembrane space
hydrogen ions
a portion of complexes I, III, IV functions as a __________
proton pump
the proton gradient formed during the ETC allows for _________ from the intermembrane space
proton diffusion
inner membrane is ___________ to protons
impermeable
protons only cross through membrane through a __________ in ATP synthase
proton channel
definition: protein complex in the cristae that also contains the active site for catalyzing the reaction ADP + P –>ATP
ATP synthase
anabolisms of ATP is endergonic but it is powered by ______ of protons
exergonic diffusion
_________ ATP are made per glucose by oxidative phorphorylation
32-34`
definition: mechanism by which ATP is made by being couples to the redox reactions of the ETC
oxidative phosphorylation
definition: biological process that removes amino groups from molecules
deamination
STEPS: proteins can be broken down to produce ATP
- amino acids must be deaminated first
- NH2 is removed and excreted as waste
- remaining carbon backbones are converted to various intermediates
STEPS: triglycerides can be broken down to produce ATP
- glycerol is phosphorylated to G3P and enters glycolysis
- fatty acids are oxidized and split into multiple 2-C acetyl groups
- each enter the citric acid cycle
Fats contain ____ energy than glucose or amino acids
more
fermentation is an _________ process
anaerobic
fermentation produces _____ during glycolysis
ATP
during fermentation only _____ ATP are made
2
during fermentation ATP is made through _________ phosphorylation
substrate level
fermentation steps
once pyruvate is produced at the end of glycolysis
1. NADH is converted back to NAD+
it is made by transferring an H from NADH
two types of fermentation
lactic acids and alcoholic fermentation
_____ uses alcoholic fermentation when deprived of oxygen
yeast
what happens during alcoholic fermentation at the end of glycolysis
pyruvate is split into 2-C ethyl alcohol and CO2
what happens during lactic acid fermentation
pyruvate is converted to 3-C lactate
__________________use lactic acid fermentation if O2 is unavailable
vertebrae muscle cells