LO13 Day 1 Flashcards
do all genes code only for proteins?
no they code for enzymes and other proteins
Linus Pauling showed what?
That a mutation in a single gene could result in a defective protein
Transcription converts what?
DNA to RNA
Translation produces what?
A polypeptide from RNA
What is the central dogma of molecular biology?
states that the nucleotide sequence of some DNA gene code for the amino acid sequence of a specific polypeptide via an RNA intermediate
Is a single stranded polymer of nucleotides
RNA
What are the two purine nitrogenous bases used in RNA
Adenine and Guanine
What two pyrimidines bases used in RNA?
Uracil and Cytosine
How is Ribose different from deoxyribose at the 2’ carbon
Has a hydroxyl group
Deoxyribose and ribose are both ______ sugars
pentose
What is at the 5’ end of RNA molecule
exposed phosphate group
What is at the 3’ end of RNA molecule?
exposed OH group
Phosphate group of a DNA or RNA nucleotide makes this molecules _____ and ____ charged
acidic and negatively
What is attached to the 1C of the ribose sugar
nitrogenous base
What bond forms between 3C of ribose and phosphate group of the next nucleotide?
covalent
mRNA is what?
messenger RNA
mRNA contain the infromation for making specific _______
proteins
mRNA is transcribed from _______________ in DNA
protein-coding genes
Definition: A set of three consecutive RNA nucleotides that specifies one amino acids
codon
3 nucleotides specify how many amino acids?
one
the number order and type of codons in a specific mRNA determines what?
the primary structure of protein
genetic code includes how many codons?
64
AUG is which codon and codes for what?
start codon and methionine
How many codons code for terminate translation?
3
The genetic code is ____ and virtually ______
redundant and universal
amino acids specified by ______________ codon
more than one
A codon never specifies ________ amino acid
more than one