Liver, Gallbladder, Pancreas, Spleen Flashcards
describe the liver and its functions
LARGEST GLAND
functions:
-carb, protein, fat metabolism
-forms bile
-destroys old red blood cells
-vitamin and iron storage
what does bile do?
mixes with chyme in stomach
needed for emulsification, absorption and digestion of fat and makes intestinal contents more alkaline
what is contained within the lesser omentum?
portal structures
what is the hepatic artery?
+ branches supply oxygenated blood to the liver = roughly 25% of liver’s blood supply
what is the portal vein?
delivers blood drained from abdominal digestive organs to the liver
delivers roughly 75% of liver’s blood supply
what is the bile duct?
delivers bile from liver (and gall bladder) to the duodenum
what does the portal (=hepatic portal) vein collect blood from?
1) gastroduodenal vein
—> craniopancreatico-duodenal vein (L lobe of pancreas and duodenum)
—> right gastroepiploic vein (greater curvature of stomach)
2) splenic vein
—> left gastroepiploic vein (greater curvature of stomach)
—> pancreatics (R lobe of pancreas)
name the 3 parts of the portal triad (flow of blood and bile within lobular liver)
1) portal areas (traids, tracts, fields)
2) hepatic sinusoids, bile canaliculi
3) centrilobular region
describe the portal areas of the portal triad
regions containing microscopic branches of the portal vein, hepatic artery and bile ductule
bile ductule lined by cuboidal cholangiocytes
describe the hepatic sinusoids/bile canaliculi of the portal triad
hepatocytes interact with venous and arterial blood in hepatic sinusoids
also secrete bile into bile canaliculi that transport bile to the bile ductules as part of the biliary system
canaliculi = channels formed by tight junctions between hepatocytes
describe the centrilobular region of the portal triad
deoxygenated, processed blood is carried to the central vein which ultimately drains into the caudal vena cava
how does the liver drain to caudal vena cava?
via hepatic veins
multiple hepatic veins drain blood from the liver –> anatomically very short
describe the functions of the gall bladder
-bile storage (from liver)
-concentration –> removal of water from electrolytes
-duodenum/jejunum release cholecystokinin that causes gallbladder to rhythmically contract and causes sphincter of the hepatopancreatic ampulla to relax in order to release bile into duodenum
-bile emulsifies fat
what does the sphincter of oddi do?
controls bile and pancreatic juice drainage
-prevents bile from entering duodenum and instead it flow up the cystic duct to gallbladder for concentration and storage
describe the mucosa in the gallbladder
simple columnar epithelium with short microvilli
Na+ and water are transported into the lamina propria as part of bile concentration