Liver Cancer Flashcards
do primary or secondary malignancies occur in the liver
both
why is it a good secondary site
big in size
vastly perfused
portal drainage
what are the two primary cancers called
Hepatocellular carcinoma
Cholangiocarcinoma
what area is targeted in Hepatocellular carcinoma
the hepatocytes (the functional cells of the liver)
Aetiology of hepatocellular carcinoma
chronic liver disease: viral hep brings about mutation of cells DNA
environmental toxins: arsenic
Manifestations
insidious onset
usually masked by some other underlying liver disease (Hep)
Treatment
poor prognosis
partial hepatectomy
chemo
radiation
How do you treat a common benign tutor found in young women
stop taking the pill
where does cholangiocarcinomas originate from
in the bile duct epithelium
what is this cancer commonly associated with
chronic inflammation of duct epithelium
Where does secondary liver cancer commonly come from
colon
lung
breast
Manifestations
hepatomegaly ascites abdominal pain anorexia fever weight loss
Treatment
poor prognosis
supportive/palliative
