Irritable Bowel Syndrome

Question 1

what is IBS

Answer 1

GI motility disorder

Question 2

Etiology

Answer 2

look at the triggers
idiopathic
linked diet, stress, smoking, lactose intolerance

Question 3

Patho

Answer 3

malabsorption of fermentable CHO and polyps (alcohol sugars) - when processed by the gut flora = gas (flatulence)

altered CNS regulation of GI motor and sensory function

molecular signalling defect for serotonin

Question 4

What is serotonin

Answer 4

neurotransmitter produced in the gut mucosa

Question 5

what is serotonins role in IBS

Answer 5

used for motility

Question 6

Manifestations

Answer 6

abdominal pain
abdominal discomfort
diarrhea or constipation
flatulence
nausea
mucoid stool

Question 7

what is mucoid stool

Answer 7

when the gut is angry it secrets more mucous (excreted in the stool)

Question 8

Diagnosis

Answer 8

exclude other disease
Presentation
Labs: BCB, CRP
Scopes: endoscopy, colonoscopy, sigmoidoscopy

Question 9

Treatment

Answer 9

based on severity and type
avoid offending foods
decrease stress
drugs to assist with manifestations: laxatives, analgesics, antibiotics with cautions (don’t want to eliminate good gut flora)