Liver

Question 1

Brings blood from intestines

Answer 1

Portal vein

Question 2

Blood flow from portal vein and hepatic artery flow into

Answer 2

Low pressure sinusoids

Question 3

AST and ALT test for

Answer 3

Hepatocyte integrity

Question 4

Serum bilirubin, alkaline phosphatase, and gamma-glutamic transpeptidase test for

Answer 4

Biliary excretion

Question 5

Serum albumin and coagulation factors test for

Answer 5

Hepatocyte synthetic fn

Question 6

Involved in AA metabolism

Answer 6

AST and ALT

Question 7

Removes phosphate groups. Seen in liver, bone, and intestine as different isozymes. Found in bile duct and liver cells. Elevated in cholestatic d/o

Answer 7

Alkaline phosphatase (ALP)

Question 8

Involved in glutathione metabolism and drug detox

Answer 8

Gamma-glutamyl transpeptidase

Question 9

GGT and ALP elevated together indicate

Answer 9

Hepatobiliary disease

Question 10

Most sensitive enzyme indicator of liver disease

Answer 10

GGT

Question 11

Most common cause of acute hepatitis

Answer 11

Viral

Question 12

Acute encephalopathy, coagulopathy, acute renal failure, GI bleeding, infection, sepsis, respiratory failure, cardiovascular collapse

Answer 12

Acute hepatitis severe cases

Question 13

Results from inadequate liver fn due to either diminished # of hepatocytes OR impaired fn

Answer 13

Acute hepatic failure

Question 14

Usually results from chronic liver disease with yrs of progressive injury

Answer 14

Acute hepatic failure

Question 15

Liver disease of short duration (within 26 wks of initial liver injury) w/o pre-existing disease

Answer 15

Acute hepatic failure

Question 16

Acute massive hepatic necrosis usually

Answer 16

Acute hepatic failure

Question 17

Reye’s syndrome, acute fatty liver of pregnancy, and tetracycline toxicity

Answer 17

Non-necrotic liver failure

Question 18

Jaundice, N/V

Answer 18

Acute hepatic failure

Question 19

Due to retention of bilirubin

Answer 19

Jaundice

Question 20

Caused by high ammonia levels. Have behavioral abnormalities, rigidity,, hyperreflexia(asterixis), and EEG changes.

Answer 20

Hepatic encephalopathy

Question 21

Decreased production of clotting factors

Answer 21

Bleeding diathesis

Question 22

Thrombocytopenia in acute hepatic failure caused by

Answer 22

Hypersplenism and marrow suppression

Question 23

DIC in acute hepatic failure because liver

Answer 23

Fails to clear activated factors from circulation

Question 24

Fatty liver of pregnancy and toxic reaction to tetracycline/valproate show

Answer 24

Microvesicular steatosis

Question 25

^^^^ AST and ALT, hypoalbuminemia, hyperammonemia

Answer 25

Acute hepatic failure

Question 26

Function renal failure w/o intrinsic morphological abnormalities. Renal fn normalizes with return of liver fn

Answer 26

Hepatorenal syndrome.

Question 27

Systemic vasodilation > compensatory renal vasoconstriction > decreased GFR

Answer 27

Hepatorenal syndrome

Question 28

Blood drainage via _______ veins > IVC

Answer 28

Hepatic