Hep C Flashcards

1
Q

Inhibits formation and activation of replication complex

A

Inhibition of NS4A

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2
Q

Enzyme responsible for cleaving and processing polypeptide

A

NS3/4A

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3
Q

Pol that mediates HCV RNA replication

A

NS5B

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4
Q

Important in replication, assembly, and secretion

A

NS5A

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5
Q

Booster for paritaprevir

A

CYP3A4

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6
Q

Essential substrate for viral RNA synthesis

A

Inosine monophosphate dehydrogenase

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7
Q

Inhibits viral RNA replication and vision assembly

A

Inhibition NS5A

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