List 4 Flashcards
thoracic duct
- drains lymph from the intestinal, lumbar, intercostal trunks, right lymphatic duct, left subclavian, left jugular, and left bronchomediastinal trunks
- originates as an enlarged sac called cisterns chlyi in the abdomen and passes upward through the diaphragm besides the aorta
right lymphatic duct
originates in the right thorax at the union of the right jugular, right subclavian, and right bronchomediastinal trunks.
lymphatic capillaries
-the walls are formed from a single layer of endothelium(simple squamous)
lymph
-Fluid derived from interstitial fluid, that the lymphatic vessels carry
lymph nodes
- mass of lymphoid tissue located along the course of a lymphatic vessel
- bean-shaped
- filters foreign particles and debris from lymph
- produces and houses lymphocytes and macrophages
osmotic pressure
-Plasma colloid osmotic pressure
edema
-excess tissue fluid(lymph formation prevents edema)
hilum
-Blood vessels and nerves join a lymph node through the indented region of the lymph node called hilium
lymph nodules
- Masses of lymphatic tissue
- lymphatic molecules
Peyer’s patches
- MALT(mucosa-associated lymphoid tissue) aggregates of lymphatic nodules
- scattered throughout the mucosal lining of the distal portion of the small intestine
thymus
- soft, bilobed gland enclosed in a connective tissue capsule
- mediastinum
- T-lymphocytes leave the thymus provide immunity
- Epithelial cells in the thymus secrete protein hormones called thymosins-stimulate maturation of T-lymphocytes
spleen
- the largest lymphatic organ
- houses macrophages; remove foreign particles, damage red blood cells, and cellular debris from blood
- contains lymphocytes
red pulp vs. white pulp
- These are the 2 types of lobules located in the spleen
- (RP) blood travels through the sinuses, with lymphocytes checking for antigens in the blood.
- (WP) equivalent of lymph nodules(clonal selection); composed of splenic nodules and are packed with lymphocytes
pathogen
-Disease causing agents the lymphatic system helps defends pathogens
non-specific defense vs. specific defense
There are three levels of defense:
- non-specific:skin, sweat, and stomach
- non-specific: complement, interferons, fever, inflammation, phagocytes
- specific: lymphocytes(T&B)
cell-mediated immunity
- Cellular immune response
- The body’s attack by T-cells and their secreted products on non-self-antigens
antibody-mediated immunity
- B-lymphocytes
- pathogen is in the body that activate B-lymphocytes. The B-lymphocytes then begin clonal selection
complement
- agglutination
- opsoniztion
- positive chemotaxis
- antigen-antibody complex
perforin
-Protein that natural killer cells release that forms pores in the cell membrane of infected cell
primary immune response vs. secondary immune response
(PIR)
-occurs when B cells and T cells become activated after 1st encountering the antigens for which they are specialized to react
(SIR)
-produced by memory B cells along with memory T cells
-immune system’s response to subsequent encounters with a non-self-antigen
cytokines
-Type of polypeptide secreted by a T-lymphocytes that enhances cellular responses to antigens
clones(clonal selection or polyclonal response)
- clonal selection: making cells that are all the same(takes place in lymph nodules)
- polyclonal response: the involvement of more than one antibody type
vaccine
-A preparation that includes an antigen that can stimulate a primary immune response against a particular pathogen but does not produce symptoms of the associated infectious disease
antigen-presenting cell
-The cell that displays an antigen to the cells of the immune system so they can defend the body against a particular antigen