List 4 Flashcards

1
Q

thoracic duct

A
  • drains lymph from the intestinal, lumbar, intercostal trunks, right lymphatic duct, left subclavian, left jugular, and left bronchomediastinal trunks
  • originates as an enlarged sac called cisterns chlyi in the abdomen and passes upward through the diaphragm besides the aorta
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2
Q

right lymphatic duct

A

originates in the right thorax at the union of the right jugular, right subclavian, and right bronchomediastinal trunks.

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3
Q

lymphatic capillaries

A

-the walls are formed from a single layer of endothelium(simple squamous)

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4
Q

lymph

A

-Fluid derived from interstitial fluid, that the lymphatic vessels carry

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5
Q

lymph nodes

A
  • mass of lymphoid tissue located along the course of a lymphatic vessel
  • bean-shaped
  • filters foreign particles and debris from lymph
  • produces and houses lymphocytes and macrophages
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6
Q

osmotic pressure

A

-Plasma colloid osmotic pressure

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7
Q

edema

A

-excess tissue fluid(lymph formation prevents edema)

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8
Q

hilum

A

-Blood vessels and nerves join a lymph node through the indented region of the lymph node called hilium

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9
Q

lymph nodules

A
  • Masses of lymphatic tissue

- lymphatic molecules

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10
Q

Peyer’s patches

A
  • MALT(mucosa-associated lymphoid tissue) aggregates of lymphatic nodules
  • scattered throughout the mucosal lining of the distal portion of the small intestine
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11
Q

thymus

A
  • soft, bilobed gland enclosed in a connective tissue capsule
  • mediastinum
  • T-lymphocytes leave the thymus provide immunity
  • Epithelial cells in the thymus secrete protein hormones called thymosins-stimulate maturation of T-lymphocytes
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12
Q

spleen

A
  • the largest lymphatic organ
  • houses macrophages; remove foreign particles, damage red blood cells, and cellular debris from blood
  • contains lymphocytes
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13
Q

red pulp vs. white pulp

A
  • These are the 2 types of lobules located in the spleen
  • (RP) blood travels through the sinuses, with lymphocytes checking for antigens in the blood.
  • (WP) equivalent of lymph nodules(clonal selection); composed of splenic nodules and are packed with lymphocytes
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14
Q

pathogen

A

-Disease causing agents the lymphatic system helps defends pathogens

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15
Q

non-specific defense vs. specific defense

A

There are three levels of defense:

  1. non-specific:skin, sweat, and stomach
  2. non-specific: complement, interferons, fever, inflammation, phagocytes
  3. specific: lymphocytes(T&B)
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16
Q

cell-mediated immunity

A
  • Cellular immune response

- The body’s attack by T-cells and their secreted products on non-self-antigens

17
Q

antibody-mediated immunity

A
  • B-lymphocytes

- pathogen is in the body that activate B-lymphocytes. The B-lymphocytes then begin clonal selection

18
Q

complement

A
  1. agglutination
  2. opsoniztion
  3. positive chemotaxis
    - antigen-antibody complex
19
Q

perforin

A

-Protein that natural killer cells release that forms pores in the cell membrane of infected cell

20
Q

primary immune response vs. secondary immune response

A

(PIR)
-occurs when B cells and T cells become activated after 1st encountering the antigens for which they are specialized to react
(SIR)
-produced by memory B cells along with memory T cells
-immune system’s response to subsequent encounters with a non-self-antigen

21
Q

cytokines

A

-Type of polypeptide secreted by a T-lymphocytes that enhances cellular responses to antigens

22
Q

clones(clonal selection or polyclonal response)

A
  • clonal selection: making cells that are all the same(takes place in lymph nodules)
  • polyclonal response: the involvement of more than one antibody type
23
Q

vaccine

A

-A preparation that includes an antigen that can stimulate a primary immune response against a particular pathogen but does not produce symptoms of the associated infectious disease

24
Q

antigen-presenting cell

A

-The cell that displays an antigen to the cells of the immune system so they can defend the body against a particular antigen

25
autoimmunity
-an immune response against a person's own tissues
26
interferons
-Are proteins that lymphocytes and fibroblasts produce in response to viruses or tumor cells
27
fever
-is a non-specific defense
28
inflammation
-is a reaction that produces localized redness, swelling, heat, and pain
29
haptens
-small molecule that combines with a larger one, forming an antigen
30
major histocompatibility complex(MHC)
- "Human leukocyte antigen(HLA) | - help T cells recognize that a newly displayed antigen is foreign, not self
31
memory cells
- B lymphocyte or T lymphocyte produced in a primary immune response that can be activated rapidly if the same antigen is encountered again - secondary immune response
32
immunoglobulins
-commonly called antibodies
33
heavy chains vs light chains
``` Heavy chains: -twice as many amino acids as the light chains -stronger -identical Light chains: -amino acid chains are identical -quicker ```
34
naturally acquired active immunity
-this form of immunity develops after primary immune response and is a response to exposure of a live pathogen(life)
35
naturally acquired passive immunity
-Fetus acquires limited immunity against pathogens for which the pregnant women have developed active immunities(breastfeeding)
36
artificially acquired active immunity
-Developed immunity by a vaccine(vaccine)
37
artificially acquired passive immunity
-immunity developed by an injection antiserum or antitoxin(Rogam)