List 2 Flashcards
hematocrit
- The 45% of red blood cells found in blood samples
erythropoiesis
- Red blood cell formation
- initially occurs in the yolk sac, liver, and spleen
hemocytoblasts
-hematopoietic stem cell; this is what we want for bone marrow transport because it has the potential to make all the blood cells
proerythroblast
-messenger RNA for hemoglobin; has a nucleus
erythroblast
contains a nucleus and is undergoing mitosis
reticulocyte
- they still have an endoplasmic reticulum making hemoglobin.
- in this stage, cells exit the bone marrow to enter the blood.
thrombopoietin
-A hormone that stimulates megakaryocytic to proliferate and yield platelets
hemoglobin
-Oxygen carrying pigment in red blood cells
bilirubin
- secreted in the bile as bile pigments
- has an orange pigment
- hemoglobins, proteins, that are not recycled are in this bile
anemia
-A deficiency of red blood cells or a reduction in that amount of hemoglobin they contain
sickle cell disease
- Cause: defective gene
- Defect: Red blood cells abnormally shaped
platelets(thrombocytes)
- not complete cells
- when exposed to collagen they form a plug, which we refer to as clotting
serotonin
-contracts smooth muscle in the vessel walls, reducing blood flow
albumins
- the smallest of the plasma proteins, yet account for 60% of these proteins by weight
- osmotic pressure of plasma
- keeps the interstitial fluid isotonic(equal)
- synthesized in the liver
fibrinogen vs. fibrin
- constitues about 4% of the plasma proteins, they play a primary role in blood coagulation(fibrinogen)
- fibrin is a protein
thrombus vs. embolus
- a blood clot abnormally forming in a vessel is a thrombus
- A clot that dislodges, or a fragment of a clot that breaks loose and is carried away by the blood flow is called an embolus
prothrombin
- alpha globulin that the liver continually produces and is thus a normal constituent of plasma.
- converts into thrombin when calcium ions are present
thrombin
-blood clotting enzyme that catalyzes formation of fibrin from fibrinogen
antigens vs. antibodies
-An antigen is any molecule that triggers an immune response. When the immune system encounters an antigen not found not he body’s own cells, it will attack that antigen by producing protein antibodies against that antigen
agglutination
-clumping of red blood cells
ABO blood groups
-based on the presence/absence of two major antigens on red blood cell membranes
Rh factor
- named after the rhesus monkey
- Rh-positve and Rh-negative
erythroblastosis fetalis
-Rh negative woman giving birth to a Rh positive baby and the issue with the positive blood circulating in the mothers blood.
diapedesis
-allows the white blood cells to leave the circulation